[1]尹肃,南凯,余红超,等.基于中医“脾肾互赞”理论探讨补肾健脾法治疗绝经后骨质疏松症的作用机理[J].中医正骨,2025,37(06):62-65.
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基于中医“脾肾互赞”理论探讨补肾健脾法治疗绝经后骨质疏松症的作用机理()

《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第37卷
期数:
2025年06期
页码:
62-65
栏目:
学术探讨
出版日期:
2025-06-20

文章信息/Info

作者:
尹肃1南凯2余红超1武倩倩1呼延晓婷1
1.陕西中医药大学,陕西 咸阳 712046; 2.西安市红会医院,陕西 西安 710054
关键词:
骨质疏松绝经后 脾肾同治 健脾 补肾 线粒体自噬
摘要:
绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)是女性绝经后雌激素水平下降引发的骨代谢失衡性疾病,属中医“骨痿”“骨枯”等范畴,其核心病因病机在于脾肾两虚所致的精微不运、骨失所养。中医“脾肾互赞”理论认为,脾肾之间具有相互协同、辅助的关系。而脾肾与线粒体之间的关系不容忽视。补肾健脾法是中医治疗PMOP的常用治法,其作用机理可能是通过调节线粒体自噬改善PMOP患者的骨代谢失衡。本文概述了脾肾互赞理论及PMOP的中医病因病机; 分析了线粒体自噬与PMOP的关系; 基于中医“脾肾互赞”理论,从脾肾与线粒体的关系、补肾健脾法对线粒体自噬的调节作用2个方面,对补肾健脾法治疗PMOP的作用机理进行了探讨。

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备注/Memo

备注/Memo:
基金项目:陕西省自然科学基础研究计划项目(2024JC-YBQN-0896); 西安市卫生健康委员会科研项目(2024qn11)
通讯作者:南凯 E-mail:drnankai@xjtu.edu.cn
更新日期/Last Update: 1900-01-01