参考文献/References:
[1] ZHAO X,XU D,LI Y,et al.MicroRNAs regulate bone metabolism[J].J Bone Miner Metab,2014,32(3):221-231.
[2] STEIN EM,KEPLEY A,WALKER M,et al.Skeletal structure in postmenopausal women with osteopenia and fractures is characterized by abnormal trabecular plates and cortical thinning[J].J Bone Miner Res,2014,29(5):1101-1109.
[3] WON Y,LIM JR,KIM YH,et al.Atypical femoral fracture combined with osteonecrosis of jaw during osteoporosis treatment with bisphosphonate[J].J Bone Metab,2014,21(2):155-159.
[4] IGASE M,KOHARA K,TABARA Y,et al.Change in arterial stiffness associated with monthly bisphosphonate treatment in women with postmenopausal osteoporosis[J].Menopause,2014,21(9):962-966.
[5] LIANG W,LI X,LI Y,et al.Tongue coating microbiome regulates the changes in tongue texture and coating in patients with post-menopausal osteoporosis of Gan-shen deficiency syndrome type[J].Int J Mol Med,2013,32(5):1069-1076.
[6] LIANG W,LIM M,LI X,et al.Icariin promotes bone formation via the BMP-2/Smad4 signal transduction pathway in the hFOB 1.19 human osteoblastic cell line[J].Int J Mol Med,2012,30(4):889-895.
[7] CROSET M,SANTINI D,IULIANI M,et al.MicroRNAs and bone metastasis:a new challenge[J].Molecules,2014,19(7):10115-10128.
[8] CHOUDHURI S.Small noncoding RNAs:biogenesis,function,and emerging significance in toxicology[J].J Biochem Mol Toxicol,2010,24(3):195-216.
[9] SIOMI H,SIOMI MC.Posttranscriptional regulation of microRNA biogenesis in animals[J].Mol Cell,2010,38(3):323-332.
[10] LEE Y,KIM M,HAN J,et al.MicroRNA genes are transcribed by RNA polymerase II[J].EMBO J,2004,23(20):4051-4060.
[11] CARTHEW RW,SONTHEIMER EJ.Origins and Mechanisms of miRNAs and siRNAs[J].Cell,2009,136(4):642-655.
[12] DENLI AM,TOPS BB,PLASTERK RH,et al.Processing of primary microRNAs by the Microprocessor complex[J].Nature,2004,432(7014):231-235.
[13] KIM VN,HAN J,SIOMI MC.Biogenesis of small RNAs in animals[J].Nat Rev Mol Cell Biol,2009,10(2):126-139.
[14] YI R,QIN Y,MACARA IG,et al.Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs[J].Genes Dev,2003,17(24):3011-3016.
[15] BOHNSACK MT,CZAPLINSKI K,GORLICH D.Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs[J].RNA,2004,10(2):185-191.
[16] HAMMOND SM,BERNSTEIN E,BEACH D,et al.An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells[J].Nature,2000,404(6775):293-296.
[17] DJURANOVIC S,NAHVI A,GREEN R.A parsimonious model for gene regulation by miRNAs[J].Science,2011,331(6017):550-553.
[18] GUO H,INGOLIA NT,WEISSMAN JS,et al.Mammalian microRNAs predominantly act to decrease target mRNA levels[J].Nature,2010,466(7308):835-840.
[19] YANG JS,MAURIN T,ROBINE N,et al.Conserved vertebrate mir-451 provides a platform for Dicer-independent,Ago2-mediated microRNA biogenesis[J].Proc Natl Acad Sci USA,2010,107(34):15163-15168.
[20] GARNERO P.New developments in biological markers of bone metabolism in osteoporosis[J].Bone,2014,66:46-55.
[21] CAO Z,MOORE BT,WANG Y,et al.MiR-422a as a potential cellular microRNA biomarker for postmenopausal osteoporosis[J].PLoS One,2014,9(5):e97098.
[22] WANG Y,LI L,MOORE BT,et al.MiR-133a in human circulating monocytes:a potential biomarker associated with postmenopausal osteoporosis[J].PLoS One,2012,7(4):e34641.
[23] LU Y,XIAO J,LIN H,et al.A single anti-microRNA antisense oligodeoxyribonucleotide(AMO)targeting multiple microRNAs offers an improved approach for microRNA interference[J].Nucleic Acids Res,2009,37(3):e24.
[24] EBERT MS,SHARP PA.MicroRNA sponges:progress and possibilities[J].RNA,2010,16(11):2043-2050.
[25] YOUNGER ST,COREY DR.Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters[J].Nucleic Acids Res,2011,39(13):5682-5691.
[26] SHI C,QI J,HUANG P,et al.MicroRNA-17/20a inhibits glucocorticoid-induced osteoclast differentiation and function through targeting RANKL expression in osteoblast cells[J].Bone,2014,68:67-75.
[27] KATO RB,ROY B,DE OLIVEIRA FS,et al.Nanotopography directs mesenchymal stem cells to osteoblast lineage through regulation of microRNA-SMAD-BMP-2 circuit[J].J Cell Physiol,2014,229(11):1690-1696.
[28] CHEN L,HOLMSTRØM K,QIU W,et al.MicroRNA-34a inhibits osteoblast differentiation and in vivo bone formation of human stromal stem cells[J].Stem Cells,2014,32(4):902-912.
[29] LUZI E,MARINI F,SALA SC,et al.Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor[J].J Bone Miner Res,2008,23(2):287-295.
[30] MIZUNO Y,YAGI K,TOKUZAWA Y,et al.miR-125b inhibits osteoblastic differentiation by down-regulation of cell proliferation[J].Biochem Biophys Res Commun,2008,368(2):267-272.
[31] HUANG J,ZHAO L,XING L,et al.MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation[J].Stem Cells,2010,28(2):357-364.
[32] ITOH T,NOZAWA Y,AKAO Y.MicroRNA-141 and-200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5[J].J Biol Chem,2009,284(29):19272-19279.
[33] INOSE H,OCHI H,KIMURA A,et al.A microRNA regulatory mechanism of osteoblast differentiation[J].Proc Natl Acad Sci USA,2009,106(49):20794-20799.
[34] KAHAI S,LEE SC,LEE DY,et al.MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7[J].PLoS One,2009,4(10):e7535.
[35] KAPINAS K,KESSLER CB,DELANY AM.miR-29 suppression of osteonectin in osteoblasts:regulation during differentiation and by canonical Wnt signaling[J].J Cell Biochem,2009,108(1):216-224.
[36] WANG T,XU Z.miR-27 promotes osteoblast differentiation by modulating Wnt signaling[J].Biochem Biophys Res Commun,2010,402(2):186-189.
[37] LI H,XIE H,LIU W,et al.A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans[J].J Clin Invest,2009,119(12):3666-3677.
[38] MIZUNO Y,TOKUZAWA Y,NINOMIYA Y,et al.miR-210 promotes osteoblastic differentiation through inhibition of AcvR1b[J].FEBS Lett,2009,583(13):2263-2268.
[39] 梁文娜,李西海,李灿东.绝经后骨质疏松的核心病机——骨痿[J].中国老年学杂志,2015,35(18):5333-5335.
[40] 梁文娜,李西海,李灿东,等.骨免疫与绝经后骨质疏松妇女骨重建失衡[J].国际骨科学杂志,2012,33(2):103-105.
[41] LI Y,LIANG W,LI X,et al.Effect of serum from postmenopausal women with osteoporosis exhibiting the Kidney-Yang deficiency pattern on bone formation in an hFOB 1.19 human osteoblastic cell line[J].Exp Ther Med,2015,10(3):1089-1095.
相似文献/References:
[1]李林军.应用膨胀式椎弓根螺钉内固定治疗合并骨质疏松的
胸腰椎退行性疾病[J].中医正骨,2015,27(08):49.
[2]李学朋,朱立国.骨疏康胶囊对去卵巢大鼠骨小梁的影响[J].中医正骨,2015,27(12):12.
LI Xuepeng,ZHU Liguo.Effect of Gushukang Jiaonang(骨疏康胶囊)on bone trabecula in the ovariectomized rats[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(10):12.
[3]陈冠军,陈扬,庄汝杰.可灌注骨水泥椎弓根螺钉系统
在老年腰椎疾患手术中的应用[J].中医正骨,2015,27(02):40.
[4]王丹辉,贲越,韩梅.林蛙油治疗绝经后骨质疏松症的临床研究[J].中医正骨,2014,26(01):27.
Wang Danhui*,Ben Yue,Han Mei..Clinical study of Rana temporaria oil in the treatment of postmenopausal osteoporosis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2014,26(10):27.
[5]黄建华,黄建武,李慧辉,等.加味左归丸对绝经后骨质疏松症肝肾不足证
患者骨密度的影响[J].中医正骨,2013,25(11):19.
Huang Jianhua*,Huang Jianwu,Li Huihui,et al.Effect of JIAWEI ZUOGUI pill on bone mineral density in postmenopausal osteoporosis patients with deficiency of liver and kidney[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2013,25(10):19.
[6]项旻,杨虹,林爱菊,等.绝经后2型糖尿病患者骨质疏松与血微量元素的关系研究[J].中医正骨,2013,25(12):20.
Xiang Min*,Yang Hong,Lin Aiju,et al.Clinical study on the relationship between osteoporosis and serum trace elements levels in postmenopausal women with type 2 diabetes[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2013,25(10):20.
[7]史晓林,李春雯,张志强.弱阳离子磁珠分离技术和基质辅助激光解吸电离飞行时间质谱技术在原发性Ⅰ型骨质疏松症血清标志蛋白筛选中的应用[J].中医正骨,2014,26(03):5.
Shi Xiaolin*,Li Chunwen,Zhang Zhiqiang..Application of magnetic beads based weak cation exchange separation technology and matrix-assisted laser desorption-ionization time of flight mass spectrometry technology in screening serum protein markers of primary type-Ⅰ osteoporosis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2014,26(10):5.
[8]李明,徐明雄,冯左基,等.自拟壮骨方治疗绝经后骨质疏松症的疗效及作用机制研究[J].中医正骨,2014,26(09):21.
Li Ming*,Xu Mingxiong,Feng Zuoji,et al.Study on the curative effect and mechanism of action of self-made ZHUANGGU decoction in treatment of postmenopausal osteoporosis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2014,26(10):21.
[9]陈俊杰,李晴晴,夏瑢.脂代谢及血清内脂素水平与绝经后骨质疏松症的
相关性研究[J].中医正骨,2012,24(04):16.
CHEN Jun-jie*,LI Qing-qing,XIA Rong.*.Study on the correlations between the levels of lipid metabolism and serum visfatin and postmenopausal osteoporosis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2012,24(10):16.
[10]许超,肖鲁伟,吴承亮.绝经后女性骨质疏松症辨证分型与抑郁焦虑的关系研究[J].中医正骨,2011,23(12):3.
XU Chao*,XIAO Lu-wei,WU Cheng-liang.*.Study on the relationship between the syndrome differ classification and the depression and anxiety for the postmenopausal women with osteoporosis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2011,23(10):3.
[11]韩艳,温利平,刘娜,等.补肾活血方对去卵巢大鼠骨代谢及骨密度的影响[J].中医正骨,2015,27(12):7.
HAN Yan,WEN Liping,LIU Na,et al.Effect of Bushen Huoxue Fang(补肾活血方)on bone metabolism and bone mineral density in the ovariectomized rats[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(10):7.
[12]欧国峰,刘鑫,董博,等.绝经后骨质疏松症的免疫学研究进展[J].中医正骨,2016,28(08):70.
[13]施振宇,刘钟,陈文亮,等.中医综合疗法防治绝经后骨量减少的多中心临床研究[J].中医正骨,2017,29(04):1.
SHI Zhenyu,LIU Zhong,CHEN Wenliang,et al.A multicenter clinical study of complex therapy of traditional Chinese medicine for prevention and treatment of postmenopausal osteopenia[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2017,29(10):1.
[14]梁文娜,李西海,胡柳,等.二至丸抑制绝经后骨质疏松大鼠骨代谢紊乱的作用机制研究[J].中医正骨,2017,29(11):1.
LIANG Wenna,LI Xihai,HU Liu,et al.Study on mechanism of action of Erzhi Wan(二至丸)in inhibiting bone metabolism disorder in rats with postmenopausal osteoporosis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2017,29(10):1.
[15]刘晨,李兴勇,姚兴璋,等.绝经后骨质疏松症的流行病学概况及发病机制研究进展[J].中医正骨,2018,30(03):52.
[16]杨依然,刘钟,毛一凡,等.酪蛋白激酶-2相互作用蛋白1基于磷脂酰肌醇3-激酶/蛋白激酶B/哺乳动物雷帕霉素靶蛋白通路参与绝经后骨质疏松症发生发展过程中细胞自噬的机制[J].中医正骨,2018,30(04):59.
[17]曹俊青,郑剑南,张麟.右归丸联合阿仑膦酸钠口服治疗绝经后骨质疏松症肾阳虚证的临床研究[J].中医正骨,2018,30(05):20.
CAO Junqing,ZHENG Jiannan,ZHANG Lin.A clinical study of oral application of Yougui Wan(右归丸)and alendronate sodium for treatment of postmenopausal osteoporosis with kidney-yang deficiency syndrome[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2018,30(10):20.
[18]李中万,徐绍俊,杨广钢,等.健肾方联合碳酸钙D3咀嚼片(Ⅱ)
治疗绝经后骨质疏松症肾阳虚证[J].中医正骨,2018,30(08):11.
LI Zhongwan,XU Shaojun,YANG Guanggang,et al.Oral application of Jianshen Fang(健肾方)and calcium carbonate and Vitamin D3 chewable tablets(Ⅱ)for treatment of postmenopausal osteoporosis with kidney-yang deficiency syndrome[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2018,30(10):11.
[19]赵凡,刘全,吴连国.口服强骨饮联合碳酸钙D3片治疗绝经后骨质疏松症的临床研究[J].中医正骨,2019,31(04):26.
ZHAO Fan,LIU Quan,WU Lianguo.Oral applications of Qianggu Yin(强骨饮)and calcium carbonate and Vitamin D3 tablets for treatment of postmenopausal osteoporosis:a clinical study[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2019,31(10):26.
[20]史晓林,杨依然,刘钟,等.基于蛋白质组学方法分析绝经后骨质疏松症全血差异蛋白[J].中医正骨,2019,31(06):7.
SHI Xiaolin,YANG Yiran,LIU Zhong,et al.Analysis of proteins which are differentially expressed in whole blood of patients with postmenopausal osteoporosis using proteomics approach[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2019,31(10):7.