[1]龚家川.影响强直性脊柱炎患者髋关节受累的危险因素分析[J].中医正骨,2017,29(06):25-27.
　GONG Jiachuan.Analysis of risk factors for affection of hip joint in patients with ankylosing spondylitis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2017,29(06):25-27.
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影响强直性脊柱炎患者髋关节受累的危险因素分析()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第29卷
期数:
2017年06期
页码:
25-27
栏目:
临床研究
出版日期:
2017-06-20

文章信息/Info

Title:
Analysis of risk factors for affection of hip joint in patients with ankylosing spondylitis
作者:
龚家川
河南省商丘市第一人民医院,河南 商丘 476100
Author(s):
GONG Jiachuan
The First People's Hospital of Shangqiu,Shangqiu 476100,Henan,China
关键词:
脊柱炎; 强直性;  髋关节;  危险因素
Keywords:
Key words spondylitis; ankylosing;  hip joint;  risk factors
摘要:
目的:探讨影响强直性脊柱炎(ankylosing spondylitis,AS)患者髋关节受累的危险因素,为临床早期干预提供依据。方法:回顾性分析94例AS患者的临床资料,根据髋关节是否受累分为髋关节受累组(36例)和髋关节未受累组(58例)。观察受累髋关节的具体情况,并比较2组患者的发病年龄、红细胞沉降率(erythrocyte sedimentation rate,ESR)、血清C反应蛋白(C-reactive protein,CRP)含量、血清免疫球蛋白G(immunoglobulin G,IgG)含量、Schober试验值及枕墙距。结果:36例髋关节受累患者中,单侧髋关节受累7例、双侧髋关节受累29例,其中37个股骨头囊性变、26个股骨头坏死、21个髋关节间隙变窄、8个髋关节纤维性强直或骨性强直。与髋关节未受累组相比,髋关节受累组的发病年龄低、ESR高、血清CRP含量和IgG含量高、Schober试验值低、枕墙距大[(21.3±2.7)岁,(31.5±5.0)岁,t=5.584,P=0.028;(47.7±29.4)mm·h-1,(31.6±12.7)mm·h-1,t=5.692,P=0.024;(52.8±31.5)mg·L-1,(33.2±23.6)mg·L-1,t=7.013,P=0.015;(29.8±10.2)g·L-1,(14.9±7.2)g·L-1,t=8.826,P=0.009;(2.4±0.9)cm,(3.2±0.7)cm,t=4.942,P=0.039;(16.3±4.4)cm,(10.2±3.8)cm,t=6.975,P=0.018]。结论:发病年龄低、ESR高、血清CRP含量和IgG含量高、Schober试验值低、枕墙距大,均可能是影响AS患者髋关节受累的危险因素。
Abstract:
ABSTRACT Objective:To explore the risk factors for affection of hip joint in patients with ankylosing spondylitis(AS)so as to provide evidence for early clinical intervention.Methods:The medical records of 94 patients with AS were analyzed retrospectively,and the patients were divided into affected hip joint group(36 cases)and unaffected hip joint group(58 cases).The affected hip joints were observed and the age of onset,erythrocyte sedimentation rate(ESR),the serum content of C-reactive protein(CRP)and immunoglobulin G(IgG),Schober values and pillow-wall distance were compared between the 2 groups.Results:Unilateral affected hip joint(7 cases)and bilateral affected hip joint(29 cases)were found in 36 patients.The hip joint damages included cystis degeneration of femoral head(37),femoral head necrosis(26),narrowed hip joint space(21)and fibrous ankylosis or bony ankylosis of hip joint(8).Compared with patients in unaffected hip joint group,patients in affected hip joint group had a lower onset age,higher ESR,higher serum contents of CRP and IgG,lower Schober values and longer pillow-wall distance(21.3+/-2.7 vs 31.5+/-5.0 years,t=5.584,P=0.028; 47.7+/-29.4 vs 31.6+/-12.7mm/h,t=5.692,P=0.024; 52.8+/-31.5 vs 33.2+/-23.6 mg/L,t=7.013,P=0.015; 29.8+/-10.2 vs 14.9+/-7.2g/L,t=8.826,P=0.009; 2.4+/-0.9 vs 3.2+/-0.7 cm,t=4.942,P=0.039; 16.3+/-4.4 vs 10.2+/-3.8 cm,t=6.975,P=0.018).Conclusion:Lower onset age,higher ESR,higher serum contents of CRP and IgG,lower Schober experimental values and longer pillow-wall distance may be risk factors for affection of hip joint in patients with AS.

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更新日期/Last Update: 2017-06-20