[1]贾琼,柴旭斌,钟炜钰.口服独活寄生汤治疗腰椎间盘突出症椎间孔镜术后感觉异常[J].中医正骨,2016,28(02):11-14.
　JIA Qiong,CHAI Xubin,ZHONG Weiyu.Oral application of Duhuo Jisheng Tang(独活寄生汤)for treatment of paresthesia after transforaminal endoscopic discectomy in patients with lumbar disk herniation[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2016,28(02):11-14.
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口服独活寄生汤治疗腰椎间盘突出症椎间孔镜术后感觉异常()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第28卷
期数:
2016年02期
页码:
11-14
栏目:
临床研究
出版日期:
2016-02-20

文章信息/Info

Title:
Oral application of Duhuo Jisheng Tang(独活寄生汤)for treatment of paresthesia after transforaminal endoscopic discectomy in patients with lumbar disk herniation
作者:
贾琼1; 柴旭斌2; 钟炜钰1
1.湖南中医药高等专科学校附属第一医院,湖南 株洲 412000;
2.河南省洛阳正骨医院/河南省骨科医院,河南 洛阳 471002
Author(s):
JIA Qiong1; CHAI Xubin2; ZHONG Weiyu1
1.The First Affiliated Hospital of Hunan college of traditional Chinese medicine,Zhuzhou 412000,Hunan,China 2.Luoyang Orthopedic-Traumatological Hospital,Luoyang 471002,Henan,China
关键词:
椎间盘移位;  腰椎;  手术后期间;  感觉异常;  椎间孔镜;  独活寄生汤
Keywords:
intervertebral disk displacement;  lumbar vertebrae;  postoperative period;  paresthesia;  transforaminal endoscope;  Duhuo Jisheng Tang
摘要:
目的:观察口服独活寄生汤治疗腰椎间盘突出症椎间孔镜术后感觉异常的临床疗效。方法:将60例腰椎间盘突出症椎间孔 镜术后感觉异常的患者随机分为2组,分别采用口服独活寄生汤及甲钴胺胶囊治疗。治疗4周后,采用疼痛视觉模拟量表(visual analogue scale,VAS)评定下肢疼痛情况,采用尼龙绳实验评定下肢麻木情况,采用Oswestry功能障碍指数(Oswestry disability index,ODI)问卷表评定腰椎功能恢复情况,采用改良MacNab标准评定临床疗效。结果:治疗前2组患者的VAS评分、 ODI评分及尼龙绳实验评分比较,组间差异均无统计学意义[(6.36±1.52)分,(6.03±1.48)分,t=0.080,P=0.936; (28.33±5.20)分,(28.03±5.42)分,t=0.219,P=0.828;(0.85±0.33)分,(0.88±0.23) 分,t=0.395,P=0.694]; 治疗4周后独活寄生汤组的VAS评分和ODI评分均低于甲钴胺胶囊组[(2.74±1.63)分, (4.69±0.92)分,t=-3.299,P=0.002;(11.67±9.14)分,(18.80±4.87)分,t=-4.369,P=0.001],尼龙绳实验评分高 于甲钴胺胶囊组[(1.65±0.33)分,(0.95±0.35)分,t=3.472,P=0.008]。独活寄生汤组优10例、良9例、可8例、差3例 ,甲钴胺胶囊组优5例、良14例、可7例、差4例,独活寄生汤组的临床疗效优于甲钴胺胶囊组(Z=-1.996,P=0.046)。结论:口服独 活寄生汤可以有效治疗腰椎间盘突出症椎间孔镜术后感觉异常,提高患者生活质量,疗效优于口服甲钴胺胶囊,值得临床推广应 用。
Abstract:
Objective:To observe the clinical curative effect of oral application of Duhuo Jisheng Tang(独活寄生 汤,DHJST)for the treatment of paresthesia after transforaminal endoscopic discectomy in patients with lumbar disk herniation(LDH).Methods:Sixty patients with paresthesia after transforaminal endoscopic discectomy were randomly divided into 2 groups and were treated with oral application of DHJST(DHJST group)and mecobalamine capsule(mecobalamine capsule group)respectively.After 4-week treatment,the lower limb pain were evaluated by using pain visual analogue scale(VAS),and the lower limb numbness were evaluated by using Nylon rope experiment,and the lumbar function were evaluated by using Oswestry disability index(ODI)questionnaires,and the clinical curative effects were evaluated by using improved MacNab standard.Results:There was no statistical difference in the VAS scores,ODI scores and Nylon rope experiment scores between the 2 groups before the treatment(6.36+/-1.52 vs 6.03+/-1.48 points,t=0.080,P=0.936; 28.33+/-5.20 vs 28.03+/-5.42 points,t=0.219,P=0.828; 0.85+/-0.33 vs 0.88+/-0.23 points,t=0.395,P=0.694).After 4-week treatment,the VAS scores and ODI scores were lower in DHJST group compared to mecobalamine capsule group(2.74+/-1.63 vs 4.69+/- 0.92 points,t=-3.299,P=0.002; 11.67+/-9.14 vs 18.80+/-4.87 points,t=-4.369,P=0.001),and the Nylon rope experiment scores were higher in DHJST group compared to mecobalamine capsule group(1.65+/-0.33 vs 0.95+/-0.35 points,t=3.472,P=0.008).Ten patients obtained an excellent result,9 good,8 fair and 3 poor in DHJST group; while 5 patients obtained an excellent result,14 good,7 fair and 4 poor in mecobalamine capsule group.The DHJST group surpassed the mecobalamine capsule group in the total curative effect(Z=- 1.996,P=0.046).Conclusion:Oral application of DHJST can effectively relieve the paresthesia after transforaminal endoscopic discectomy in patients with LDH and improve the life quality of the patients,and it surpasses the mecobalamine capsule in the curative effect,so it is worthy of popularizing in clinic.

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通讯作者:柴旭斌 E-mail:28130487@qq.com
更新日期/Last Update: 2016-04-30