[1]齐宏哲,郭涛,高淦.手法复位联合经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折的疗效和安全性Meta分析[J].中医正骨,2024,36(03):36-41.
　QI Hongzhe,GUO Tao,GAO Gan.Clinical outcome and safety of manipulative reduction combined with percutaneous kyphoplasty for treatment of osteoporotic vertebral compression fracture:a meta-analysis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2024,36(03):36-41.
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手法复位联合经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折的疗效和安全性Meta分析()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第36卷
期数:
2024年03期
页码:
36-41
栏目:
文献研究
出版日期:
2024-03-20

文章信息/Info

Title:
Clinical outcome and safety of manipulative reduction combined with percutaneous kyphoplasty for treatment of osteoporotic vertebral compression fracture:a meta-analysis
作者:
齐宏哲1; 郭涛2; 高淦2
1.贵州中医药大学,贵州 贵阳 550002; 2.贵州省人民医院,贵州 贵阳 550002
Author(s):
QI Hongzhe1; GUO Tao2; GAO Gan2
1.Guizhou University of Traditional Chinese Medicine,Guiyang 550002,Guizhou,China 2.Guizhou Provincial People's Hospital,Guiyang 550002,Guizhou,China
关键词:
脊柱骨折;  骨质疏松性骨折;  骨折; 压缩性;  后凸成形术;  正骨手法;  专题Meta分析
Keywords:
spinal fractures;  osteoporotic fractures;  fractures; compression;  kyphoplasty;  bone setting manipulation;  Meta-analysis as topic
摘要:
目的:系统评价手法复位联合经皮椎体后凸成形术(percutaneous kyphoplasty,PKP)治疗骨质疏松性椎体压缩骨折(osteoporotic vertebral compression fracture,OVCF)的疗效与安全性。方法:应用计算机检索中国知网、维普网、万方数据库、PubMed及Cochrane Library中关于手法复位联合PKP治疗OVCF的临床对照试验研究文献(观察组干预措施为手法复位联合PKP,对照组干预措施为单纯PKP)。检索时限均为建库至2023年10月1日。根据文献纳入和排除标准对检索到的文献进行筛选后,对纳入文献进行质量评价,提取文献中的数据进行Meta分析。结果:共检索出文献233篇,经筛选后最终纳入文献9篇,均为中文文献。Meta分析结果显示,观察组疼痛视觉模拟量表评分低于对照组[MD=-0.67,95%CI(-1.15,-0.20),P=0.006],伤椎后凸Cobb角改善和椎体前缘高度的恢复均优于对照组[MD=-1.54,95%CI(-2.67,-0.41),P=0.007; MD=2.81,95%CI(2.02,3.59),P=0.000],但2组在Oswestry功能障碍指数和骨水泥渗漏率方面的差异均无统计学意义[MD=-3.99,95%CI(-11.24,3.26),P=0.280; OR=0.48,95%CI(0.21,1.11),P=0.080]。结论:手法复位联合PKP治疗OVCF可有效缓解患者疼痛、改善伤椎后凸畸形、恢复伤椎前缘高度,疗效优于单纯采用PKP治疗,但二者在患者日常活动能力改善及安全性方面相当。
Abstract:
Objective:To systematically review the clinical outcome and safety of manipulative reduction combined with percutaneous kyphoplasty(PKP)for treatment of osteoporotic vertebral compression fracture(OVCF).Methods:All the clinical controlled trial articles about manipulative reduction combined with PKP for treatment of OVCF included from database's inception to October 1,2023 were retrieved from the China National Knowledge Infrastructure,Vip Database,Wanfang Database,PubMed and Cochrane Library through computer.The patients in observation group were treated with manipulative reduction and PKP,while the ones in control group with PKP alone.The articles were screened according to the inclusion and exclusion criteria.The methodological quality of researches in the included articles was evaluated,and then a Meta-analysis was conducted.Results:Two hundred and thirty-three articles were searched out.After screening,9 Chinese articles were included in the final analysis.The results of Meta-analysis revealed that the pain visual analogue scale(VAS)score was lower,the improvement of kyphotic Cobb angle of injured vertebrae and restoration of anterior border height of vertebral body were better in observation group compared to control group(MD=-0.67,95%CI(-1.15,-0.20),P=0.006; MD=-1.54,95%CI(-2.67,-0.41),P=0.007; MD=2.81,95%CI(2.02,3.59),P=0.000); while,the comparison of Oswestry disability index(ODI)and bone cement leakage incidence rate between the 2 groups revealed no significant differences(MD=-3.99,95%CI(-11.24,3.26),P=0.280; OR=0.48,95%CI(0.21,1.11),P=0.080).Conclusion:Manipulative reduction combined with PKP can effectively relieve pain,improve the kyphosis of injured vertebrae,and restore the anterior border height of injured vertebrae in treatment of OVCF,and its curative outcome is better than that of PKP alone; while,both are similar to each other in the improvement of activities of daily living and safety.

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通讯作者:郭涛 E-mail:guotao04b@sina.com
更新日期/Last Update: 1900-01-01