[1]郭玉星,熊辉,周彪,等.Nod样受体家族含pyrin结构域蛋白3 和嘌呤能离子通道型受体7在急性痛风性 关节炎发病中的作用研究进展[J].中医正骨,2018,30(08):39-41.
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Nod样受体家族含pyrin结构域蛋白3 和嘌呤能离子通道型受体7在急性痛风性 关节炎发病中的作用研究进展()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第30卷
期数:
2018年08期
页码:
39-41
栏目:
综 述
出版日期:
2018-08-20

文章信息/Info

作者:
郭玉星1熊辉2周彪2朱方晓2邵先舫3易法银2王国佐3向黎黎4
1.湖南中医药大学附属中西医结合医院,湖南 长沙 410006; 2.湖南中医药大学,湖南 长沙 410208; 3.湖南中医药大学附属常德医院,湖南 常德 415000; 4.湖南中医药大学第二附属医院,湖南 长沙 410005
关键词:
关节炎痛风性 受体嘌呤能P2X7 NLRP3 综述
摘要:
Nod样受体家族含pyrin结构域蛋白3(Nod-like receptor family pyrin domain-containing protein 3,NLRP3)和嘌呤能离子通道型受体7(purinergic P2X7 receptor,P2X7R)是近年发现的炎症小体,在多种疾病的发病过程中发挥着重要作用。为了探讨急性痛风性关节炎的发病机制,本文对NLRP3及其在急性痛风性关节炎发病中的作用、P2X7R及其在急性痛风性关节炎发病中的作用、NLRP3和P2X7R的关系以及二者在急性痛风性关节炎发病中的协同作用进行了综述。

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金项目(81574005); 湖南省卫生计生委课题(20180781); 湖南省长沙市省市科卫联合科研课题项目(2017225); 湖南省湘潭市医学科研项目(2018xtyx-12) 通讯作者:邵先舫 E-mail:826389265@qq.com
更新日期/Last Update: 2018-08-31