[1]董一平,袁强,张宁,等.外泌体在股骨头坏死诊治中的应用[J].中医正骨,2023,35(01):47-52.
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外泌体在股骨头坏死诊治中的应用()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期数:
2023年01期
页码:
47-52
栏目:
综述
出版日期:
2023-01-20

文章信息/Info

作者:
董一平1袁强1张宁2张颖3
(1.河南中医药大学研究生院,河南 郑州 450046; 2.湖南中医药大学研究生院,湖南 长沙 410208; 3.河南省洛阳正骨医院/河南省骨科医院,河南 洛阳 471002)
关键词:
股骨头坏死 外泌体 综述
摘要:
股骨头坏死(osteonecrosis of the femoral head,ONFH)是一种常见的骨科疾病,发病机制复杂,目前临床上的治疗方法并不令人满意。外泌体是细胞分泌的具有双层膜的细胞外囊泡,内含丰富的蛋白质与核酸分子。外泌体在血清中的含量及外泌体内miRNA的差异性能够反映ONFH的发生阶段; 而不同细胞来源的外泌体能够通过调控信号传导和相关基因表达影响骨细胞、血管细胞的增殖分化,进而影响骨重塑。因此,外泌体在ONFH的诊治方面具有重要的应用价值。本文对外泌体进行了概述,对外泌体在ONFH诊断和治疗中的应用价值进行了综述。

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中医正骨2023年1月第35卷第1期 J Trad Chin Orthop Trauma,2023,Vol.35,No.1(总051)
(总052)中医正骨2023年1月第35卷第1期 J Trad Chin Orthop Trauma,2023,Vol.35,No.1
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(收稿日期:2022-03-27 本文编辑:吕宁)

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金项目(81774348)通讯作者:张颖 E-mail:xylrw5@163.com
更新日期/Last Update: 1900-01-01