[1]孟愿,石瑛,詹红生.肠道菌群介导调节性T细胞影响骨代谢的研究进[J].中医正骨,2023,35(01):43-46.
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肠道菌群介导调节性T细胞影响骨代谢的研究进()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期数:
2023年01期
页码:
43-46
栏目:
综述
出版日期:
2023-01-20

文章信息/Info

作者:
孟愿石瑛詹红生
(上海中医药大学附属曙光医院,上海 201203)
关键词:
胃肠道微生物群 T-淋巴细胞 骨生成 骨质吸收 综述
摘要:
人体肠道内的微生物构成了复杂的肠道微生态系统。肠道菌群能够通过免疫系统调节、代谢产物分泌等多个途径影响骨代谢。调节性T细胞是T细胞的一个特殊亚群,其介导的免疫抑制在骨代谢过程中起重要作用。肠道菌群能够影响调节性T细胞的分化与功能,进而影响骨代谢。本文对调节性T细胞进行了概述,并从肠道菌群对调节性T细胞的影响及调节性T细胞对骨形成、骨吸收的影响等方面对肠道菌群介导调节性T细胞影响骨代谢的研究进展进行了综述。

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备注/Memo

备注/Memo:
基金项目:上海市临床重点专科“中医骨伤科学”建设项目(shslczdzk03901); 上海市慢性筋骨病临床医学研究中心项目(20MC1920600)通讯作者:石瑛 E-mail:shiying1974@126.com
更新日期/Last Update: 1900-01-01