[1]张建乔,曾忠友,宋国浩,等.经皮椎体强化联合后路经肌间隙入路短节段椎弓根螺钉固定治疗无神经损伤的Ⅲ期Kmmell病[J].中医正骨,2018,30(02):54-58.
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经皮椎体强化联合后路经肌间隙入路短节段椎弓根螺钉固定治疗无神经损伤的Ⅲ期Kümmell病()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第30卷
期数:
2018年02期
页码:
54-58
栏目:
临床报道
出版日期:
2018-02-20

文章信息/Info

作者:
张建乔; 曾忠友; 宋国浩; 俞伟; 籍剑飞; 宋永兴
中国人民武装警察部队浙江省总队嘉兴医院,浙江 嘉兴 314033
关键词:
脊柱骨折;  Kü; mmell病;  骨质疏松;  椎体成形术;  椎体后凸成形术;  骨折固定术
摘要:
目的:探讨经皮椎体强化联合后路经肌间隙入路短节段椎弓根螺钉固定治疗无神经损伤的Ⅲ期Kümmell病的临床疗效和安全性。方法:2014年9月至2016年9月收治21例Ⅲ期Kümmell病患者。男2例,女19例; 年龄60～82岁,中位数75岁; 均为单椎体病变,其中T11病变3例、T12病变5例、L1病变9例、L2病变2例、L3病变2例; 3例有轻微外伤史,其余18例均无明显外伤史; 腰椎骨密度(双能X线吸收法测定)T值<-2.5; 合并非相邻椎体陈旧性骨折3例,腰椎退行性侧弯2例,Ⅱ型糖尿病13例,高血压病21例,慢性支气管炎8例,尿毒症1例; 均无脊髓和(或)神经根受压症状,均未合并严重心肺功能及凝血功能障碍、恶性肿瘤。应用抗骨质疏松药物及非甾体类抗炎药治疗2周无效。均采用经皮椎体成形术或经皮椎体后凸成形术联合后路经肌间隙入路短节段椎弓根螺钉固定术治疗。记录患者的手术时间、出血量,分别于术前、术后7 d及末次随访时评定患者的疼痛视觉模拟量表(visual analogue scale,VAS)评分、Oswestry功能障碍指数(Oswestry disability index,ODI)、后凸Cobb角及伤椎前、后缘高度,同时观察治疗及随访期间并发症的发生情况。结果:21例患者均顺利完成手术。手术时间60～95 min,中位数75 min; 出血量20～50 mL,中位数35 mL。所有患者均获得随访,随访时间12～25个月,中位数18个月。切口均甲级愈合,均未发生脊髓神经损伤、肺栓塞、心脑血管意外、内固定松动及骨水泥团块移位等并发症。7例发生骨水泥渗漏,其中椎体周围渗漏6例、椎间盘内渗漏1例,随访期间均未出现相应临床症状。患者术前、术后7 d及末次随访时的疼痛VAS评分[(8.0±0.9)分,(2.0±0.5)分,(1.8±0.4)分]、ODI[(82.3±2.0)%,(30.9±1.3)%,(20.9±1.3)%]、伤椎前缘高度[(50.5±7.0)%,(74.6±7.9)%,(72.4±7.6)%]、伤椎后缘高度[(72.6±5.1)%,(81.4±5.1)%,(79.0±4.8)%]及后凸Cobb角(19.4°±2.5°,10.5°±2.3°,11.3°±2.0°)总体比较,各时间点之间的差异均有统计学意义(F=680.300,P=0.000; F=9 534.000,P=0.000; F=66.540,P=0.000; F=17.470,P=0.000; F=95.770,P=0.000)。术后7 d和末次随访时的VAS评分、ODI、后凸Cobb角均小于术前(P=0.017,P=0.012; P=0.001,P=0.001; P=0.001,P=0.001),伤椎前缘高度、伤椎后缘高度均大于术前(P=0.001,P=0.002; P=0.001,P=0.001); 末次随访时的ODI小于术后7 d(P=0.002),VAS评分、伤椎前缘高度、伤椎后缘高度及后凸Cobb角与术后7 d比较,差异均无统计学意义(P=0.430; P=0.630; P=0.270; P=0.460)。结论:对于无神经损伤的Ⅲ期Kümmell病,采用经皮椎体强化联合后路经肌间隙入路短节段椎弓根螺钉固定治疗,能有效减轻疼痛、恢复伤椎高度、纠正后凸畸形、改善腰部功能,并能在短期内维持伤椎高度及Cobb角,而且具有较高的安全性。

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更新日期/Last Update: 2018-07-02