[1]邵先舫,刘志军,陈绍军,等.愈髋丸代替愈髋饮治疗中青年股骨颈骨折的可行性研究[J].中医正骨,2012,24(01):18-20.
　SHAO Xian-fang*,LIU Zhi-jun,CHEN Shao-jun,et al.Study on the feasibility of treatment of femoral neck fractures in the young and middle aged through YUKUAN PILL instead of YUKUAN DRINK[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2012,24(01):18-20.
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愈髋丸代替愈髋饮治疗中青年股骨颈骨折的可行性研究()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第24卷
期数:
2012年01期
页码:
18-20
栏目:
临床研究
出版日期:
2012-01-31

文章信息/Info

Title:
Study on the feasibility of treatment of femoral neck fractures in the young and middle aged through YUKUAN PILL instead of YUKUAN DRINK
作者:
邵先舫; 刘志军; 陈绍军; 孔祥建; 张宏波; 李前
湖南省常德市第一中医院,湖南 常德 415000
Author(s):
SHAO Xian-fang*; LIU Zhi-jun; CHEN Shao-jun; KONG Xiang-jian; ZHANG Hong-bo; LI Qian.
*The First Traditional Chinese Medical Hospital of Changde City,Changde 415000,Hunan,China
关键词:
股骨颈骨折 愈髋丸 愈髋饮 治疗; 临床研究性
Keywords:
Femoral neck fractures;  YUKUAN PILL;  YUKUAN DRINK;  Therapies; investigational
摘要:
目的:对比观察愈髋丸和愈髋饮治疗中青年股骨颈骨折的临床疗效,探讨愈髋丸代替愈髋饮治疗中青年股骨颈骨折的可行性。方法:将符合要求的100例中青年股骨颈骨折患者随机分为愈髋丸组和愈髋饮组,每组50例。2组患者均采用切开复位空心钉内固定加带旋髂深血管蒂髂骨瓣植骨术,并于术后当天开始按事先分组给药,即愈髋丸组患者口服愈髋丸,愈髋饮组患者服用愈髋饮。6周后比较2组患者的症状体征、临床疗效及安全性。结果:①2组患者的症状体征比较,差异无统计学意义(Z=-1.035,P=0.301)。②2组患者的临床疗效比较,差异无统计学意义(Z=-4.234,P=0.662)。③治疗期间愈髋丸组有1例出现胃脘不适,改为餐后30 min服药后缓解; 愈髋饮组2例出现胃部饱胀,1例发生腹泻。2组患者不良反应发生率比较,差异无统计学意义(P=0.617)。结论:愈髋丸保持了愈髋饮的原有功效,具有较高的安全性,同时也解决了愈髋饮剂型落后带来的问题,在临床应用中可以代替愈髋饮使用。
Abstract:
Objective:To compare the clinical curative effects of YUKUAN PILL with that of YUKUAN DRINK in the treatment of femoral neck fractures(FNF)in the young and middle aged,and to explore the feasibility of YUKUAN PILL in the treatment of FNF instead of YUKUAN DRINK.Methods:One hundred young and middle aged patients with FNF were randomly divided into YUKUAN PILL group(group YP)and YUKUAN DRINK group(group YD),50 cases in each group.All the patients in the 2 groups were processed with open reduction and internal fixation with hollow screw and bone grafting of iliac flap with deep circumflex iliac vessel pedicle.Patients in group YP were administrated with YUKUAN PILL on the day after the operation,while the others in group YD were administrated with YUKUAN DRINK on the same day.Six months later,the symptoms and signs,clinical curative effects and safety were compared between the 2 groups.Results:①There was no statistical difference in symptoms and signs between the 2 groups(Z=-1.035,P=0.301).②There was no statistical difference in clinical curative effects between the 2 groups(Z=-4.234,P=0.662).③During the treatment period,one patient with epigastric discomfort were found in group YP and relieved after changing the administration time to postprandial 30 minutes,and two patients with stomach fullness and one patient with diarrhea were found in group YD.There was no statistical difference in incidence of adverse reaction between the 2 groups(P=0.617).Conclusion:YUKUAN PILL can maintain original effectiveness and safety of YUKUAN DRINK.Meanwhile,those problems caused by backward dosage form were solved.As a result,YUKUAN PILL can take the place of YUKUAN DRINK in the clinic.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:湖南省常德市科技局科技项目(2010SK10)
通讯作者:李前 E-mail:13787862698@139.com
更新日期/Last Update: 2012-01-20