[1]梅其杰,袁长深,段戡,等.壮药骨痹方烫熨联合运动疗法治疗膝骨关节炎的临床研究[J].中医正骨,2015,27(07):27-30.
　MEI Qijie,YUAN Changshen,DUAN Kan,et al.Clinical study of the curative effect of hot compressing and rubbing with packet of Gubi Fang(骨痹方)combined with exercise therapy in the treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(07):27-30.
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壮药骨痹方烫熨联合运动疗法治疗膝骨关节炎的临床研究()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第27卷
期数:
2015年07期
页码:
27-30
栏目:
膝骨关节炎
出版日期:
2015-07-31

文章信息/Info

Title:
Clinical study of the curative effect of hot compressing and rubbing with packet of Gubi Fang(骨痹方)combined with exercise therapy in the treatment of knee osteoarthritis
作者:
梅其杰1; 袁长深1; 段戡1; 黄肖华1; 陈劲1; 姚弘毅2
1.广西中医药大学第一附属医院,广西 南宁 530023;
2.华中科技大学附属梨园医院,湖北 武汉 430077
Author(s):
MEI Qijie1; YUAN Changshen1; DUAN Kan1; HUANG Xiaohua1; CHEN Jin1; YAO Hongyi2
1.The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530023,Guangxi,China
2.Liyuan Hospital Affiliated to Huazhong University of Science and Technology,Wuhan 430077,Hubei,China
关键词:
骨关节炎; 膝;  壮药;  熨法;  运动疗法;  治疗; 临床研究性
Keywords:
osteoarthritis; knee;  ZHUANG DRUGS;  hot packet therapy;  exercise therapy;  therapies; investigational
摘要:
目的:观察壮药骨痹方烫熨联合运动疗法治疗膝骨关节炎的临床疗效。方法:将60例膝骨关节炎患者随机分为4组,每组15例,分别采用壮药骨痹方烫熨联合运动疗法、运动疗法、口服双氯芬酸钠联合运动疗法、壮药骨痹方烫熨治疗。分别于治疗前、治疗2周后及治疗8周后,记录并比较4组患者徒手肌力检查(manual muscle testing,MMT)评分和美国膝关节协会评分(knee society score,KSS)。结果:治疗前后不同时间点间MMT评分比较,差异有统计学意义,存在时间效应(F=5.068,P=0.004); 4组患者MMT评分比较,组间差异有统计学意义,存在分组效应(F=2.086,P=0.033); 治疗前4组患者MMT评分比较,组间差异无统计学意义[(70.0±16.9)分,(70.0±19.4)分,(71.7±16.0)分,(71.7±18.6)分,F=2.086,P=0.100]; 治疗2周后和治疗8周后,壮药骨痹方烫熨联合运动疗法组MMT评分均高于运动疗法组、口服双氯芬酸钠联合运动疗法组、壮药骨痹方烫熨组[(90.0±12.7)分,(88.0±14.8)分,(88.3±12.9)分,(86.1±13.4)分,F=3.846,P=0.014;(95.0±10.4)分,(90.0±10.4)分,(91.3±11.4)分,(88.3±14.8)分,F=12.570,P=0.000]; 时间因素和分组因素存在交互效应(F=5.016,P=0.002)。治疗前后不同时间点间KSS评分比较,差异有统计学意义,存在时间效应(F=53.860,P=0.000); 4组患者KSS评分比较,组间差异有统计学意义,存在分组效应(F=528.816,P=0.000); 治疗前4组患者KSS评分比较,组间差异无统计学意义[(144.0±5.6)分,(143.0±6.3)分,(144.0±5.7)分,(143.0±6.1)分, F=0.048,P=0.986]; 治疗2周后和治疗8周后,壮药骨痹方烫熨联合运动疗法组KSS评分均高于运动疗法组、口服双氯芬酸钠联合运动疗法组、壮药骨痹方烫熨组[(253.0±5.5)分,(238.0±6.8)分,(243.0±5.7)分,(233.0±6.0)分,F=528.816,P=0.000;(263.0±5.7)分,(234.0±6.5)分,(234.0±3.7)分,(225.0±6.6)分,F=125.620,P=0.000]; 时间因素和分组因素存在交互效应(F=5.008,P=0.002)。结论:壮药骨痹方烫熨联合运动疗法治疗膝骨关节炎,能够改善膝关节功能,提高股四头肌肌力,疗效优于单纯运动疗法、单纯壮药骨痹方烫熨和口服双氯芬酸钠联合运动疗法,值得临床推广应用。
Abstract:
Objective:To observe the curative effect of hot compressing and rubbing with packet of a sort of ZHUANG drug named Gubi Fang(骨痹方,GBF)combined with exercise therapy in the treatment of knee osteoarthritis(KOA).Method:Sixty patients with KOA were randomly divided into 4 groups,15 cases in each group.The patients were treated with the combination of hot compressing and rubbing with packet of GBF and exercise therapy(GBF and exercise group),exercise monotherapy(exercise group),combination of oral administration of diclofenac sodium and exercise therapy(DFN and exercise group)and monotherapy of hot compressing and rubbing with packet of GBF(GBF group)respectively.Manual muscle testing(MMT)score and American knee society score(KSS)of the 4 groups were recorded and compared with each other before the treatment,at 2 and 8 weeks after the treatment respectively.Results:There was statistical difference in MMT score between different time points,in other words,there was time effect(F=5.068,P=0.004).There was statistical difference in MMT score between the 4 groups,in other words,there was grouping effect(F=2.086,P=0.033).No statistical difference was found between the 4 groups in MMT score before the treatment(70.0+/-16.9,70.0+/-19.4,71.7+/-16.0,71.7+/-18.6 points,F= 2.086,P=0.100).At 2 and 8 weeks after the treatment,MMT score was higher in GBF and exercise group compared to exercise group,DFN and exercise group and GBF group(90.0+/-12.7,88.0+/-14.8,88.3+/-12.9,86.1+/-13.4 points,F=3.846,P=0.014; 95.0+/-10.4,90.0+/-10.4,91.3+/-11.4,88.3+/-14.8 points,F=12.570,P=0.000),and there was interaction between time factor and grouping factor(F=5.016,P=0.002).There was statistical difference in KSS between different time points,in other words,there was time effect(F=53.860,P=0.000).There was statistical difference in KSS between the 4 groups,in other words,there was grouping effect(F=528.816,P=0.000).No statistical difference was found in KSS between the 4 groups before the treatment(144.0+/-5.6,143.0+/-6.3,144.0+/-5.7,143.0+/-6.1 points,F=0.048,P=0.986).At 2 and 8 weeks after the treatment,KSS was higher in GBF and exercise group compared to exercise group,DFN and exercise group and GBF group(253.0+/-5.5,238.0+/-6.8,243.0+/-5.7,233.0+/-6.0 points,F=528.816,P=0.000; 263.0+/-5.7,234.0+/-6.5,234.0+/-3.7,225.0+/-6.6 points,F=125.620,P=0.000),and there was interaction between time factor and grouping factor(F=5.008,P=0.002).Conclusion:Hot compressing and rubbing with packet of GBF combined with exercise therapy can improve the knee function and strengthen the quadriceps femoris,and it has a better curative effect on KOA compared to exercise monotherapy,GBF monotherapy and combination of oral administration of diclofenac sodium with exercise therapy,so it is worthy of popularizing in clinic.

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备注/Memo

备注/Memo:
2015-01-14收稿 2015-03-19修回
基金项目:华中科技大学自主创新基金项目(2014QN070)
通讯作者:姚弘毅 E-mail:yaohongyi168@163.com
更新日期/Last Update: 2015-07-30