[1]黄伟军,潘雅丽,李志民,等.抗骨增生胶囊口服联合玻璃酸钠关节腔注射治疗膝骨关节炎[J].中医正骨,2017,29(04):67-68.
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抗骨增生胶囊口服联合玻璃酸钠关节腔注射治疗膝骨关节炎()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第29卷
期数:
2017年04期
页码:
67-68
栏目:
临床报道
出版日期:
2017-04-20

文章信息/Info

作者:
黄伟军潘雅丽李志民张泽玉
浙江新安国际医院,浙江 嘉兴 314000
关键词:
骨关节炎 注射关节内 透明质酸 抗骨增生胶囊
摘要:
目的:观察抗骨增生胶囊口服联合玻璃酸钠关节腔注射治疗膝骨关节炎的临床疗效及安全性。方法:2013年11月至2015年12月,采用抗骨增生胶囊口服联合玻璃酸钠关节腔注射治疗膝骨关节炎患者50例,男28例、女22例。年龄29~51岁,中位数41岁。均为双膝骨关节炎。病程6~11年,中位数8年。抗骨增生胶囊口服,每次5粒,每日3次,连续服用4周; 玻璃酸钠注射液膝关节腔内注射,每次2 mL,每周1次,连续注射4周。治疗4周后分别采用视觉模拟量表(visual analogue scale,VAS)、Lequesne指数及关节炎影响测定量表(the arthritis impact measurement scale,AIMS)评价膝部疼痛、膝关节功能恢复及患者生活质量改善情况。治疗过程中观察不良反应发生情况。结果:治疗4周后,所有患者的膝关节疼痛VAS评分、Lequesne指数及AIMS评分均较治疗前下降[(5.55±1.01)分,(2.37±0.82)分,t=24.444,P=0.000;(13.78±2.45)分,(5.33±1.41)分,t=29.893,P=0.000;(15.42±3.44)分,(5.98±2.79)分,t=21.312,P=0.000]。2例患者出现纳食减少,对症治疗后好转。均未出现膝关节肿胀及感觉异常等不良反应。结论:抗骨增生胶囊口服联合玻璃酸钠关节腔注射治疗膝骨关节炎,能有效缓解膝部疼痛、促进膝关节功能恢复、改善患者生活质量,且安全性较高,值得临床推广应用。

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更新日期/Last Update: 1900-01-01