[1]李益军,梁兴森,方细霞,等.电针与温针灸治疗早中期膝骨关节炎的比较研究[J].中医正骨,2023,35(09):12-16.
 LI Yijun,LIANG Xingsen,FANG Xixia,et al.A comparative study of electroacupuncture therapy versus needle-warming moxibustion therapy for treatment of early- and mid-stage knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2023,35(09):12-16.
点击复制

电针与温针灸治疗早中期膝骨关节炎的比较研究()
分享到:

《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期数:
2023年09期
页码:
12-16
栏目:
临床研究
出版日期:
2023-09-20

文章信息/Info

Title:
A comparative study of electroacupuncture therapy versus needle-warming moxibustion therapy for treatment of early- and mid-stage knee osteoarthritis
作者:
李益军1梁兴森2方细霞1肖文良1李义凯3谢美玲1李嘉4李玲4高彦平3
1.东莞市石碣医院,广东 东莞 523290; 2.广州体育学院,广东 广州 510500; 3.南方医科大学第三附属医院,广东 广州 510630; 4.广东省人民医院,广东 广州 510080
Author(s):
LI Yijun1LIANG Xingsen2FANG Xixia1XIAO Wenliang1LI Yikai3XIE Meiling1LI Jia4LI Ling4GAO Yanping3
1.Shijie Hospital of Dongguan City,Dongguan 523290,Guangdong,China2.Guangzhou Sport University,Guangzhou 510500,Guangdong,China3.The Third Affiliated Hospital of Southern Medical University,Guangzhou 510630,Guangdong,China4.Guangdong Provincial People's Hospital,Guangzhou 510080,Guangdong,China
关键词:
骨关节炎 针灸疗法 电针 温针疗法
Keywords:
osteoarthritisknee acupuncture moxibustion therapy electroacupuncture needle warming therapy
摘要:
目的:比较电针与温针灸治疗早中期膝骨关节炎(knee osteoarthritis,KOA)的临床疗效。方法:将符合要求的62例早中期KOA患者随机分为电针组和温针灸组,每组31例。电针组采用电针联合常规康复训练治疗,温针灸组采用温针灸联合常规康复训练治疗。2组患者均每周治疗3次,共治疗4周。记录并比较治疗前和治疗结束时2组患者膝关节疼痛视觉模拟量表(visual analogue scale,VAS)评分、汉密尔顿抑郁量表(Hamilton depression rating scale,HAMD)评分、Lysholm膝关节评分及膝关节损伤和骨关节炎结果评分(knee injury and osteoarthritis outcome score,KOOS)。结果:电针组退出2例,温针灸组退出1例。治疗结束时,2组患者膝关节疼痛VAS评分、HAMD评分均低于治疗前[膝关节疼痛VAS评分:(6.33±1.32)分,(1.33±1.02)分,t=46.637,P=0.000;(6.21±1.29)分,(2.03±1.09)分,t=47.990,P=0.000; HAMD评分:(33.91±5.23)分,(13.67 ±3.34)分,t=19.765,P=0.000;(34.35±4.32)分,(16.56 ±4.23)分,t=17.124,P=0.000],温针灸组患者膝关节疼痛VAS评分、HAMD评分均低于电针组(t=-2.548,P=0.014; t=11.708,P=0.000); 2组患者Lysholm膝关节评分、KOOS均高于治疗前[Lysholm膝关节评分:(52.47±2.78)分,(80.17 ±1.69)分,t=23.653,P=0.000;(50.84±2.57)分,(78.93 ±1.86)分,t=22.768,P=0.000; KOOS:(81.94 ±13.76)分,(122.78±21.69)分,t=25.674,P=0.000;(82.75 ±14.68)分,(114.56±23.85)分,t=22.241,P=0.000],温针灸组患者Lysholm膝关节评分、KOOS均高于电针组(t=7.726,P=0.000; t=13.426,P=0.000)。结论:对于早中期KOA,温针灸较电针能更好地缓解患者抑郁情绪、减轻膝关节疼痛和改善膝关节功能。
Abstract:
Objective:To compare the clinical outcomes of electroacupuncture(EA)therapy versus needle-warming moxibustion(NWM)therapy in treatment of early- and mid-stage knee osteoarthritis(KOA).Methods:Sixty-two patients with early- and mid-stage KOA were enrolled in the study and were randomly divided into EA therapy group and NWM therapy group,31 cases in each group.The patients in EA therapy group were treated with EA therapy and conventional rehabilitation training,and the ones in NWM therapy group with NWM therapy and conventional rehabilitation training.All patients were treated three times a week for consecutive 4 weeks.The knee pain visual analogue scale(VAS)score,Hamilton depression rating scale(HAMD)score,Lysholm knee score(LKS)and knee injury and osteoarthritis outcome score(KOOS)were recorded and compared between the 2 groups before the treatment and at the end of treatment respectively.Results:Two patients in EA therapy group and 1 case in NWM therapy group dropped out of the study.The knee pain VAS score and HAMD score decreased at the end of treatment compared to pretreatment in the 2 groups(knee pain VAS score:6.33±1.32 vs 1.33±1.02 points,t=46.637,P=0.000; 6.21±1.29 vs 2.03±1.09 points,t=47.990,P=0.000; HAMD score:33.91±5.23 vs 13.67±3.34 points,t=19.765,P=0.000; 34.35±4.32 vs 16.56±4.23 points,t=17.124,P=0.000),and they both were lower in NWM therapy group compared to EA therapy group(t=-2.548,P=0.014; t=11.708,P=0.000); while the LKS and KOOS increased at the end of treatment compared to pretreatment in the 2 groups(LKS:52.47±2.78 vs 80.17±1.69 points,t=23.653,P=0.000; 50.84±2.57 vs 78.93±1.86 points,t=22.768,P=0.000; KOOS:81.94±13.76 vs 122.78±21.69 points,t=25.674,P=0.000; 82.75±14.68 vs 114.56±23.85 points,t=22.241,P=0.000),and they both were higher in NWM therapy group compared to EA therapy group(t=7.726,P=0.000; t=13.426,P=0.000).Conclusion:The NWM therapy can better relieve depression,alleviate knee pain and improve knee function compared to EA therapy in treatment of early- and mid-stage KOA.

参考文献/References:

[1] OUSSEDIK S,ABDEL M P,VICTOR J,et al.Alignment in total knee arthroplasty[J].2020,102-B(3):276-279.
[2] JANG S,LEE K,JU J H.Recent updates of diagnosis,pathophysiology,and treatment on osteoarthritis of the knee[J].Int J Mol Sci,2021,22(5):2619.
[3] ALRAWASHDEH W,ESCHWEILER J,MIGLIORINI F,et al.Effectiveness of total knee arthroplasty rehabilitation programmes:a systematic review and meta-analysis[J].J Rehabil Med,2021,53(6):jrm00200.
[4] SHI X,YU W,ZHANG W,et al.A comparison of the effects of electroacupuncture versus transcutaneous electrical nerve stimulation for pain control in knee osteoarthritis:a Bayesian network meta-analysis of randomized controlled trials[J].Acupunct Med,2021,39(3):163-174.
[5] SHI G X,TU J F,WANG T Q,et al.Effect of electro-acupuncture(EA)and manual acupuncture(MA)on markers of inflammation in knee osteoarthritis[J].J Pain Res,2020,13:2171-2179.
[6] ALTMAN R,ASCH E,BLOCH D,et al.Development of criteria for the classification and reporting of osteoarthritis:classification of osteoarthritis of the knee[J].Arthritis Rheum,1986,29(8):1039-1049.
[7] HAMILTON M.The assessment of anxiety states by rating[J].Br J Med Psychol,1959,32(1):50-55.
[8] LYSHOLM J,GILLQUIST J.Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale[J].Am J Sports Med,1982,10(3):150-154.
[9] ROOS E M,ROOS H P,LOHMANDER L S,et al.Knee injury and osteoarthritis outcome score(KOSS):development of a selfadministered outcome measure[J].J Orthop Sports Phys Ther,1988,28(2):88-96.
[10] LAVAND'HOMME P M,KEHLET H,RAWAL N,et al.Pain management after total knee arthroplasty:procedure specific postoperative pain managemenT recommendations[J].Eur J Anaesthesiol,2022,39(9):743-757.
[11] GAZENDAM A,ZHU M,CHANG Y,et al.Virtual reality rehabilitation following total knee arthroplasty:a systematic review and meta-analysis of randomized controlled trials[J].Knee Surg Sports Traumatol Arthrosc,2022,30(8):2548-2555.
[12] 高洁,欧阳八四,张音,等.电针与温针灸治疗肾虚髓亏型膝骨关节炎疗效比较[J].中国针灸,2012,32(5):395-398.
[13] 陈瑜,贾叶娟,吕九亨,等.不同刺灸法治疗膝骨关节炎的临床疗效观察[J].针刺研究,2020,45(7):569-573.
[14] 滕春光.温针灸与电针治疗膝关节骨性关节炎临床疗效对比观察[J].中医临床研究,2012,4(12):34-35.
[15] 王娟.电针与温针灸治疗瘀血阻滞型膝关节骨性关节炎的研究[J].检验医学与临床,2017,14(4):508-509.
[16] WANG T Q,LI L R,TAN C X,et al.Effect of electroacupuncture on gut microbiota in participants with knee osteoarthritis[J].Front Cell Infect Microbiol,2021,11:597431.
[17] WANG Q,LV H,SUN Z T,et al.Effect of electroacupuncture versus sham electroacupuncture in patients with knee osteoarthritis:a pilot randomized controlled trial[J].Evid Based Complement Alternat Med,2020,2020:1686952.
[18] 张家媛,姜涛,林晓东,等.基于“脾病而四肢不用”理论从脾论治早期膝骨关节炎的理论探讨[J].中医正骨,2022,34(7):63-65.
[19] 赵启刚,谭雪,黄艳峰,等.基于经筋理论探讨针灸治疗膝骨关节炎的作用机制[J].中医正骨,2022,34(5):75-77.
[20] 邱峰,周爱珍,过琳,等.膝骨关节炎经筋辨证的研究进展[J].中医正骨,2022,34(11):62-68.
[21] LIU W,FAN Y,WU Y,et al.Efficacy of acupuncture-re-lated therapy in the treatment of knee osteoarthritis:a network meta-analysis of randomized controlled trials[J].J Pain Res,2021,14:2209-2228.
[22] ZHANG W,ZHANG L,YANG S,et al.Electroacupuncture ameliorates knee osteoarthritis in rats via inhibiting NLRP3 inflammasome and reducing pyroptosis[J].Mol Pain,2023,19:17448069221147792.
[23] TONG J,DENG C,SUN G,et al.Electroacupuncture upregulates HIF-1α and SOX9 expression in knee osteoarthritis[J].Evid Based Complement Alternat Med,2021,2021:2047097.

相似文献/References:

[1]樊庆阳,任凯晶.定制3D打印切模辅助全膝关节置换术治疗 膝骨关节炎合并股骨干骨折畸形愈合[J].中医正骨,2015,27(11):37.
[2]刘晓雅,孙永强,刘国杰.主动快速康复锻炼对全膝关节置换术后关节活动度的影响[J].中医正骨,2015,27(09):73.
[3]郑春松,叶蕻芝,李西海,等.透骨消痛胶囊中补肾柔肝药和活血祛风药治疗 骨关节炎作用方式的计算机模拟比较[J].中医正骨,2015,27(07):6.
 ZHENG Chunsong,YE Hongzhi,LI Xihai,et al.Comparison of the mode of action of Bushen Rougan(补肾柔肝)drugs versus Huoxue Qufeng(活血祛风)drugs contained in Tougu Xiaotong Jiaonang(透骨消痛胶囊)for the treatment of osteoarthritis:A computer simulation study[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):6.
[4]宋兵华,孙俊英,倪增良,等.全膝关节置换术前CT测量股骨后髁角的临床意义[J].中医正骨,2015,27(07):38.
[5]郑春松,叶蕻芝,李西海,等.独活寄生汤含药血清对白细胞介素1β诱导的 退变关节软骨细胞中基质金属蛋白酶 和环氧化酶2表达的影响[J].中医正骨,2015,27(12):1.
 ZHENG Chunsong,YE Hongzhi,LI Xihai,et al.Impact of Duhuo Jisheng Tang(独活寄生汤)medicated serum on expression of matrix metalloproteinase and cyclooxygenase 2 in degenerative articular chondrocytes induced by interleukin-1 beta[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):1.
[6]王金良,孙京涛,李玲,等.骨水泥联合螺钉修复全膝关节置换术中 胫骨平台内侧骨缺损[J].中医正骨,2015,27(12):55.
[7]冯荣,王平,李炳奇,等.铍针刺络拔罐结合中药口服治疗膝骨关节炎合并 原发性血小板增多症1例[J].中医正骨,2015,27(12):73.
[8]蔡云仙.围手术期耳穴按压联合平衡针疗法 在全膝关节置换术后镇痛中的应用[J].中医正骨,2015,27(06):41.
[9]张荣,王健.人工全膝关节置换术的围手术期心理护理[J].中医正骨,2015,27(05):77.
[10]喻长纯,杨明路,王战朝.不同手术方式治疗胫骨平台骨折畸形愈合的体会[J].中医正骨,2015,27(03):37.
[11]孟维娜,明立功,王新德,等.关节镜下清理联合腓骨近1/3段截骨治疗膝骨关节炎[J].中医正骨,2015,27(11):40.
[12]明立功,孟维娜,王新德,等.腓骨近端截骨治疗内侧间室膝骨关节炎的近期疗效观察[J].中医正骨,2015,27(10):25.
[13]张杰,王人彦,张玉柱.膝骨关节炎的治疗进展[J].中医正骨,2015,27(10):68.
[14]梁朝,蔡静怡,闫立,等.针刀疗法改善膝骨关节炎早期疼痛症状的疗效评价[J].中医正骨,2015,27(09):9.
 LIANG Zhao,CAI Jingyi,YAN Li,et al.Evaluation of the curative effect of needle-knife therapy for relieving knee pain in patients with early knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):9.
[15]王建武,党建军,李强,等.四联疗法治疗膝骨关节炎[J].中医正骨,2015,27(08):44.
[16]刘红娟,郭会利,郭树农.云克联合中药治疗膝骨关节炎的护理[J].中医正骨,2015,27(08):75.
[17]陈卫衡.探索建立系统的膝骨关节炎中医临床科研范式 和理论体系[J].中医正骨,2015,27(07):1.
[18]帅波,沈霖,杨艳萍,等.加味青娥丸治疗膝骨关节炎的作用机制研究[J].中医正骨,2015,27(07):15.
 SHUAI Bo,SHEN Lin,YANG Yanping,et al.Study on the mechanism of action of Jiawei Qing'e Wan(加味青娥丸)for the treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):15.
[19]梅其杰,袁长深,段戡,等.壮药骨痹方烫熨联合运动疗法治疗膝骨关节炎的临床研究[J].中医正骨,2015,27(07):27.
 MEI Qijie,YUAN Changshen,DUAN Kan,et al.Clinical study of the curative effect of hot compressing and rubbing with packet of Gubi Fang(骨痹方)combined with exercise therapy in the treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):27.
[20]王丹辉,张燕,刘丽娟,等.重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白 关节腔注射联合中药薰洗治疗膝骨关节炎的临床研究[J].中医正骨,2015,27(07):31.
 WANG Danhui,ZHANG Yan,LIU Lijuan,et al.Clinical study on intra-articular injection of TypeⅡrecombinant human tumor necrosis factor receptor-Fc fusion protein combined with Chinese herbal steaming and washing therapy for treatment of knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(09):31.

备注/Memo

备注/Memo:
基金项目:东莞市社会科技发展(重点)项目(202050715011167)
通讯作者:李义凯 E-mail:ortho@smu.edu.cn
更新日期/Last Update: 1900-01-01