[1]鞠昌军,严伟,姜红江,等.自体细胞生长因子关节腔注射联合佩戴人工膝关节支具治疗膝骨关节炎[J].中医正骨,2016,28(09):46-48.
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自体细胞生长因子关节腔注射联合佩戴人工膝关节支具治疗膝骨关节炎()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第28卷
期数:
2016年09期
页码:
46-48
栏目:
膝骨关节炎
出版日期:
2016-09-20

文章信息/Info

作者:
鞠昌军严伟姜红江高广凌宋修刚秦立武
山东省文登整骨医院,山东 文登 264400
关键词:
骨关节炎 注射关节内 自体细胞生长因子 体外人工膝关节
摘要:
目的:观察自体细胞生长因子关节腔注射联合佩戴人工膝关节支具治疗膝骨关节炎的临床疗效及安全性。方法:2014年6月至2015年3月,采用自体细胞生长因子关节腔注射联合佩戴人工膝关节支具治疗膝骨关节炎患者36例,男8例、女28例。年龄49~67岁,中位数55岁。病程4~24个月,中位数15.5个月。分别于治疗前及治疗开始后1 d、1个月、3个月、6个月测定患者的西安大略和麦克马斯特大学(Western Ontario and McMaster Universities,WOMAC)骨关节炎指数评分,比较治疗前及治疗开始后6个月的膝关节内侧胫股关节间隙宽度,观察不良反应和并发症发生情况。结果:所有患者均获随访,随访时间6~12个月,中位数8个月。治疗及随访过程中均未出现任何不良反应和并发症。WOMAC骨关节炎指数评分,治疗前(46.5±7.3)分,治疗开始后1 d(40.4±6.5)分、1个月(32.2±4.7)分、3个月(30.5±5.1)分、6个月(27.8±4.6)分。治疗开始后6个月膝关节内侧胫股关节间隙宽度大于治疗前[(2.2±0.6)mm,(3.3±0.5)mm,t=8.450,P=0.000]。结论:自体细胞生长因子关节腔注射联合佩戴人工膝关节支具治疗膝骨关节炎,能够有效改善膝关节功能、增大内侧胫股关节间隙,且安全性好,值得临床推广应用。

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备注/Memo

备注/Memo:
2016-05-04收稿 2016-07-16修回
基金项目:山东省威海市科技发展计划项目(2015GNS048)
姜红江 E-mail:cjcj82006@163.com

更新日期/Last Update: 1900-01-01