[1]易林,热米拉·艾买提,张文豪,等.中药基于核因子-κB信号通路治疗骨关节炎作用机制的研究进展[J].中医正骨,2023,35(09):49-52.
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中药基于核因子-κB信号通路治疗骨关节炎作用机制的研究进展()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期数:
2023年09期
页码:
49-52
栏目:
综述
出版日期:
2023-09-20

文章信息/Info

作者:
易林热米拉·艾买提张文豪向文远邓迎杰方锐
新疆医科大学附属中医医院,新疆 乌鲁木齐 830000
关键词:
骨关节炎 中药 NF-κB 信号传导 综述
摘要:
骨关节炎(osteoarthritis,OA)是一种临床上常见的慢性退行性关节疾病。核因子-κB(nuclear factor-κB,NF-κB)信号通路参与机体的免疫应答、炎症反应、细胞分化、细胞凋亡等多种生物过程,与OA的发生发展关系密切。中药在改善OA症状方面疗效显著,而中药治疗OA的作用机制与抑制NF-κB信号通路的异常激活关系密切。本文概述了NF-κB信号通路,探讨了NF-κB信号通路与OA的关系,对中药基于NF-κB信号通路治疗OA作用机制的研究进展进行了综述。

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备注/Memo

备注/Memo:
基金项目:新疆维吾尔自治区重点研发计划项目(2021B03006-2); 新疆维吾尔自治区自然科学基金项目(2022D01C170,2022D01C171)
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更新日期/Last Update: 1900-01-01