[1]王啸华,谢林.椎间盘退变的生物疗法研究进展[J].中医正骨,2023,35(07):40-45.
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椎间盘退变的生物疗法研究进展()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第35卷
期数:
2023年07期
页码:
40-45
栏目:
综述
出版日期:
2023-07-20

文章信息/Info

作者:
王啸华谢林
(南京中医药大学附属中西医结合医院,江苏 南京 210028)
关键词:
椎间盘退化 生物疗法 综述
摘要:
椎间盘退变(intervertebral disc degeneration,IDD)是造成脊柱不稳的主要因素之一,尽管目前学术界尚未就IDD的具体机制达成共识,但研究者一直在从多个角度寻求相关的治疗方法。生物疗法被认为可以恢复退变椎间盘的生物力学特性,并促进其内源性再生,是目前研究的热点。本文概述了IDD的基本机制,并对小分子疗法、干细胞疗法、基因疗法及组织工程疗法等IDD生物疗法的研究进展进行了综述,以期为IDD的临床治疗提供新的思路。

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备注/Memo

备注/Memo:
基金项目:江苏省中医药科技发展计划项目(ZD202008) 通讯作者:谢林 E-mail:xielin@njucm.edu.cn
更新日期/Last Update: 1900-01-01