参考文献/References:
[1] KHORASANIZADEH M,YOUSEFIFARD M,ESKIAN M,et al.Neurological recovery following traumatic spinal cord injury:a systematic review and meta-analysis[J].J Neurosurg Spine,2019,15:1-17.
[2] BACKX A P M,SPOOREN A I F,BONGERS-JANSSEN H M H,et al.Quality of life,burden and satisfaction with care in caregivers of patients with a spinal cord injury during and after rehabilitation[J].Spinal cord,2018,56(9):890-899.
[3] KATOH H,YOKOTA K,FEHLINGS M G.Regeneration of spinal cord connectivity through stem cell transplantation and biomaterial scaffolds[J].Front Cell Neurosci,2019,13:248.
[4] GE L,ARUL K,IKPEZE T,et al.Traumatic and nontraumatic spinal cord injuries[J].World Neurosurg,2018,111:e142-e148.
[5] ANJUM A,YAZID M D,DAUD M F,et al.Spinal cord injury:pathophysiology,multimolecular interactions,and underlying recovery mechanisms[J].IntJMolSci,2020,21(20):7533.
[6] CHEN X,CHEN H,HE Y,et al.Proteomics-guided study on buyang huanwu decoction for its neuroprotective and neurogenic mechanisms for transient ischemic stroke:involvements of EGFR/PI3K/Akt/Bad/14-3-3 and Jak2/Stat3/Cyclin D1 signaling cascades[J].Mol Neurobiol,2020,57(10):4305-4321.
[7] 冯雪枫,李慢中,詹宇,等.补阳还五汤促进脑缺血大鼠脑组织微结构重塑的作用[J].北京中医药大学学报,2021,44(6):500-509.
[8] 齐英娜,谭明生,王延雷,等.补阳还五汤对大鼠急性上颈脊髓损伤后血小板活化因子的影响[J].中国骨伤,2018,31(2):170-174.
[9] BARTOSZEWSKI R,MOSZYNSKA A,SEROCKI M,et al.Primary endothelial cell-specific regulation of hypoxia-inducible factor(HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia[J].FASEB J,2019,33(7):7929-7941.
[10] MELINCOVICI C S,BOSCA A B,SUSMAN S,et al.Vascular endothelial growth factor(VEGF)-key factor in normal and pathological angiogenesis[J].Rom J Morphol Embryo,2018,59(2):455-467.
[11] 乔若飞,李俊杰,梁舒涵,等.补阳还五汤对SD大鼠脊髓损伤后HIF-1α、VEGF表达的影响[J].中医药导报,2018,24(14):30-34.
[12] SALVAGNO G L,SANCHIS-GOMAR F,PICANZA A,et al.Red blood cell distribution width:a simple parameter with multiple clinical applications[J].Crit Rev Clin Lab Sci,2015,52(2):86-105.
[13] 徐道志,王茜,杨铁柱,等.补阳还五汤对颈髓损伤患者红细胞分布宽度及急性生理与慢性健康状况评分系统Ⅱ的影响[J].中国中医急症,2020,29(3):498-500.
[14] NIGHTINGALE T E,BHANGU G S,BILZON J L J,et al.A cross-sectional comparison between cardiorespiratory fitness,level of lesion and red blood cell distribution width in adults with chronic spinal cord injury[J].J Sci Medi Sport,2020,23(2):106-111.
[15] 吴晓光.补阳还五汤对脑出血大鼠PI3K/AKT信号通路及AQP4水通道蛋白表达的影响[J].神经药理学报,2018,8(6):34.
[16] LIN W P,XIONG G P,LIN Q,et al.Heme oxygenase-1 promotes neuron survival through down-regulation of neuronal NLRP1 expression after spinal cord injury[J].J Neuroinflammation,2016,13(1):52.
[17] TAN C C,ZHANG J G,TAN M S,et al.NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model[J].J Neuroinflammation,2015,12(1):18.
[18] 李亚锋,王延雷,宋继鹏,等.补阳还五汤对急性脊髓损伤大鼠NOD样受体蛋白1/半胱氨酸蛋白水解酶-1细胞焦亡通路的影响[J].中国中医骨伤科杂志,2020,28(4):6-9.
[19] 丁洁,徐天睿,范筱.补阳还五汤调控脊髓损伤后NLRP3炎症体介导炎症反应的机制[J].国际中医中药杂志,2020,42(6):552-556.
[20] 董贤慧,谢红林,贺小平,等.补阳还五汤对脊髓损伤大鼠脊髓组织Caspase-3表达的影响[J].广东医学,2015,36(1):55-57.
[21] 齐英娜,谭明生,王延雷,等.补阳还五汤对急性脊髓损伤大鼠内质网应激相关因子影响的研究[J].中国中医骨伤科杂志,2018,26(2):8-12.
[22] 诸葛陆杰,方燕,金华倩,等.补阳还五汤上调miR-199a-5p表达促进脑缺血大鼠神经发生和血管生成[J].浙江大学学报(医学版),2020,49(6):687-696.
[23] 董贤慧,贺小平,孙淑红,等.BYHWD对脊髓损伤大鼠脊髓组织Bcl-2和Bax表达的影响[J].神经解剖学杂志,2014,30(6):677-682.
[24] 郭晓辉,卜保献,李艳侠,等.补阳还五汤对脊髓缺血再灌注损伤后细胞自噬相关蛋白影响的研究[J].新中医,2020,52(7):33-36.
[25] 裴冬阳.补阳还五汤对急性脊髓损伤患者血清MBP含量影响的临床研究[D].福州:福建中医药大学,2017.
[26] CHEN K,MARSH B C,COWAN M,et al.Sequential therapy of anti-Nogo-A antibody treatment and treadmill training leads to cumulative improvements after spinal cord injury in rats[J].Exp Neurol,2017,292:135-144.
[27] 陈恬恬,马丙祥,张晰,等.中药基于髓鞘相关抑制因子促神经再生作用靶点的研究进展[J].中国药房,2020,31(13):1654-1658.
[28] JOSET A,DODD D A,HALEGOUA S,et al.Pincher-gene-rated Nogo-A endosomes mediate growth cone collapse and retrograde signaling[J].J Cell Biol,2010,188(2):271-285.
[29] LIU S,SANDNER B,SCHACKEL T,et al.Regulated viral BDNF delivery in combination with Schwann cells promotes axonal regeneration through capillary alginate hydrogels after spinal cord injury[J].Acta Biomater,2017,60:167-180.
[30] 裴俐锋.联合应用游泳训练和补阳还五汤对大鼠全横断脊髓损伤后Nogo-A、BDNF及VEGF表达的影响[D].锦州:锦州医科大学,2018.
[31] 刘建春,张红珍,郭文娟,等.补阳还五汤对自身免疫性脑脊髓炎模型小鼠神经保护作用的机制探讨[J].中国实验方剂学杂志,2019,25(14):55-61.
[32] 范瑜洁,聂颖,陈安,等.补阳还五汤对脊髓损伤大鼠红核神经元L-型钙通道的影响[J].中医药导报,2018,24(20):26-29.
[33] 林晓敏,潘伟滨,吴玉琼,等.补阳还五汤对脊髓损伤后Ⅰ型胶原蛋白和Ⅳ型胶原蛋白表达的影响[J].中国组织工程研究,2019,23(31):4986-4991.
[34] 李俊杰,林斌,彭奇,等.补阳还五汤对大鼠脊髓损伤后BMPRⅠa,Ⅱ表达的影响[J].中国中医骨伤科杂志,2016,24(4):7-11.
[35] 邹礼梁,王奎,满夏楠,等.补阳还五汤对大鼠脊髓损伤修复与运动功能康复的作用研究[J].云南中医学院学报,2016,39(4):1-5.
[36] 赵鹏,饶耀剑,崔泽升,等.补阳还五汤对BMP2/4介导轴突再髓鞘化的影响[J].中国中医药现代远程教育,2015,13(3):144-145.
[37] 罗金鑫,黄勇.补阳还五汤含药血清对少突胶质前体细胞分化的影响[J].广州中医药大学学报,2018,35(6):1073-1078.
[38] 巫芳华,刘玉莲,高宇容,等.补阳还五汤通过甲酰肽受体2减轻大鼠脑缺血再灌注后氧化应激损伤[J].中国实验方剂学杂志,2021,27(18):9-15.
[39] 范婷婷,万彩云,卢青青,等.补阳还五汤改善脊髓损伤的抗氧化功能及作用机制[J].世界中医药,2021,16(12):1818-1823.
[40] 邵阳,杨俊锋,马勇,等.中药复方脊髓康促进脊髓损伤大鼠神经功能恢复的实验研究[J].环球中医药,2020,13(9):1479-1483.
[41] 汪今朝,张俐.活血通督汤抑制脊髓损伤后炎症反应的实验研究[J].中国中医骨伤科杂志,2019,27(7):1-5.
[42] 刘杨,高玉亭,苗宇船.丹参注射液对大鼠脊髓损伤后脑源性神经营养因子及胰岛素样生长因子-1表达的影响[J].上海交通大学学报(医学版),2018,38(3):272-275.
[43] 魏桂财,吴伟芳,郑忠,等.姜黄素对小鼠急性创伤性脊髓损伤后神经功能影响研究[J].海峡药学,2020,32(12):16-19.
(收稿日期:2021-09-14 本文编辑:时红磊)
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