[1]杜彪,韩星敏,刘艳,等.超级骨显像影像学特征诊断恶性肿瘤骨转移和代谢性骨病的应用价值[J].中医正骨,2022,34(07):46-47.
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超级骨显像影像学特征诊断恶性肿瘤骨转移和代谢性骨病的应用价值()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第34卷
期数:
2022年07期
页码:
46-47
栏目:
影像诊断
出版日期:
2022-07-20

文章信息/Info

作者:
杜彪; 韩星敏; 刘艳; 谢新立; 王旭; 刘保平
(郑州大学第一附属医院,河南 郑州 450052)
关键词:
肿瘤转移;  骨疾病; 代谢性;  放射性核素显像;  影像学特征
摘要:
目的:探讨超级骨显像影像学特征诊断恶性肿瘤骨转移和代谢性骨病的应用价值。方法:纳入299例全身骨显像检查表现为超级骨显像患者的病例资料。男223例,女76例。年龄22～86岁,中位数67岁。临床诊断确诊恶性肿瘤骨转移246例、代谢性骨病53例。由3名高年资核医学医师分析患者的超级骨显像图像,根据恶性肿瘤骨转移和代谢性骨病的超级骨显像影像学特征判断患者疾病,统计诊断结果,与临床诊断确诊结果比较,分别计算恶性肿瘤骨转移和代谢性骨病的超级骨显像影像学特征诊断相应疾病的敏感度、特异度、阳性预测值和阴性预测值。结果:超级骨显像影像学特征诊断恶性肿瘤骨转移的敏感度为91.87%、特异度为85.96%、阳性预测值为96.58%、阴性预测值为71.01%,超级骨显像影像学特征诊断代谢性骨病的敏感度为84.91%、特异度为92.00%、阳性预测值为69.23%、阴性预测值为96.64%。结论:超级骨显像影像学特征诊断恶性肿瘤骨转移和代谢性骨病具有一定的应用价值。

参考文献/References:

[1] 程艳,罗丽萍,胡珊,等.骨显像剂异常浓聚程度及前列腺癌骨转移预测模型的单中心研究[J].中华肿瘤杂志,2020,42(10):876-881.
[2] PETERSEN L J,MORTENSEN J C,BERTELSEN H,et al.Computer-assisted interpretation of planar whole-body bone scintigraphy in patients with newly diagnosed prostate cancer[J].Nucl Med Commun,2015,36(7):679-685.
[3] BIELICKAITE J,ZADEIKAITE R,JURKIENE N,et al.Comparison of serum prostate specific antigen levels and bone scintigraphy in patients with prostate carcinoma[J].Medicina(Kaunas),2003,39(9):867-871.
[4] BORO H,GOYAL A,NAIK S S,et al.Primary Sj?gren's syndrome manifesting as sclerotic metabolic bone disease[J/OL].BMJ Case Rep,2021,14(1)[2021-02-24].https://pubmed.ncbi.nlm.nih.gov/33431459/.
[5] KRISHNAPPA B,JADHAV S R,LILA A R,et al.Tumour-induced osteomalacia due to an intra-abdominal mesenchymal tumour[J/OL].BMJ Case Rep,2019,12(12)[2021-02-24].https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904179/.
[6] 曾令鹏,罗侃莹,张庆,等.58例超级骨显像分析[J].中国临床医学影像杂志,2020,31(6):446-449.
[7] 曾令鹏,张庆,关晏星,等.POEMS综合征骨显像表现为超级骨显像1例[J].中国临床医学影像杂志,2020,31(1):74-75.
[8] 任静芸,李燕,罗亚平.超级骨显像的鉴别诊断一例[J].中华核医学与分子影像杂志,2019,39(1):39-40.
[9] KULKARNI M,SONI A,SHETKAR S,et al.Coexistent superscan and Lincoln sign on bone scintigraphy[J].Clin Nucl Med,2017,42(8):630-632.
[10] 安锐,黄钢.核医学[M].3版.北京:人民卫生出版社,2015:241-247.
[11] 黄建敏,潘莉萍,刘晓梅,等.骨扫描中的超级骨显像[J].中国临床医学影像杂志,2009,20(9):711-713.
[12] BUCKLEY O,O'KEEFFE S,GEOGHEGAN T,et al.99mTc bone scintigraphy superscans:a review[J].Nucl Med Commun,2007,28(7):521-527.
[13] HARSHMAN L K,LATIFI H R,GRIFFETH L K.Visualization of discrete sacral foramina as an ancillary sign of superscan[J].Clin Nucl Med,2011,36(1):21-24.
[14] PACCOU J,PFLIMLIN A,GLOWACKI F,et al.A challen-ging case of tumor-induced osteomalacia[J].Am J Med,2021,134(1):e60-e61.
[15] LIN C Y,CHEN Y W,CHANG C C,et al.Bone metastasis versus bone marrow metastasis?Integration of diagnosis by(18)F-fluorodeoxyglucose positron emission/computed tomography in advanced malignancy with super bone scan:two case reports and literature review[J].Kaohsiung J Med Sci,2013,29(4):229-233.
[16] 王立兴,朱吉高,刘娟.肾性骨病的影像诊断分析[J].广西中医学院学报,2010,13(1):34-35.
[17] LACOMBE J M,ROPER R J.Skeletal dynamics of down syndrome:a developing perspective[J/OL].Bone,2020,133[2021-02-24].https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044033/.

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备注/Memo

备注/Memo:
通讯作者:刘保平 E-mail:liubp5000@sina.com
更新日期/Last Update: 1900-01-01