参考文献/References:
[1] LANG N,YUAN S,WANG L,et al.Epidemiological survey of ossification of the ligamentum flavum in thoracic spine:CT imaging observation of 993 cases[J].Eur Spine J,2013,22(4):857-862.
[2] LIU Y,ZHAO Y,CHEN Y,et al.RUNX2 polymorphisms associated with OPLL and OLF in the Han population[J].Clin Orthop Relat Res,2010,468(12):3333-3341.
[3] KUDO S,ONO M,RUSSELL WJ.Ossification of thoracic ligamentaflava[J].AJR Am J Roentgenol,1983,141(1):117-121.
[4] CHEN Q,YANG L,WANG L,et al.Surgery for thoracic myelopathy caused by ossification of the ligamentum flavum[J].J Clin Neurosci,2009,16(10):1316-1320.
[5] GUO JJ,LUK KD,KARPPINEN J,et al.Prevalence,distribution,and morphology of ossification of the ligamentum flavum:a population study of one thousand seven hundred thirty-six magnetic resonance imaging scans[J].Spine(Phila Pa 1976),2010,35(1):51-56.
[6] KI AD,SONG L,HO MS,et al.Ossification of the ligamentum flavum[J].Asian Spine J,2014,8(1):89-96.
[7] NAKAGAWA H.Pathophysiology and surgical strategies in the management of the ossified spinal ligaments[J].World Neurosurg,2011,75(3/4):443-444.
[8] HUR H,LEE JK,LEE JH,et al.Thoracic myelopathy caused by ossification of the ligamentum flavum[J].J Korean Neurosurg Soc,2009,46(3):189-194.
[9] 彭传刚,杨琦,李鹏.青年与老年人脊柱黄韧带的力学特性[J].中国老年学杂志,2013,9(18):4455-4456.
[10] PARK JY,CHIN DK,KIM KS,et al.Thoracic ligament ossification in patients with cervical ossification of the posterior longitudinal ligaments: tandem ossification in the cervical and thoracic spine[J].Spine(Phila Pa 1976),2008,33(13):E407-E410.
[11] HONSAWEK S,POONPUKDEE J,CHALERMPANPIPAT C,et al.Hypertrophy of the ligamentum flavum in lumbar spinal canal stenosis is associated with increased bFGF expression[J].Int Orthop,2013,37(7):1387-1392.
[12] JAYAKUMAR N,DEVI I,BHAT I,et al.Thoracic cord compression due to ossified hypertrophied ligamentum flavum[J].Neurol India,2002,50(3):286-289.
[13] CHEN J,WANG XW,Wang C,et al.Rotational stress:role in development of ossification of posterior longitudinal ligament and ligamentum flavum[J].Med Hypotheses,2011,76(1):73-76.
中医正骨2017年2月第29卷第2期 J Trad Chin Orthop Trauma,2017,Vol.29,No.2(总107)
(总108)中医正骨2017年2月第29卷第2期 J Trad Chin Orthop Trauma,2017,Vol.29,No.2
[14] CAI HX,YAYAMA T,UCHIDA K,et al.Cyclic tensile strain facilitates the ossification of ligamentum flavum through β-catenin signaling pathway:in vitro analysis[J].Spine(Phila Pa 1976),2012,37(11):E639-E646.
[15] TSUKAMOTO N,MAEDA T,MIURA H,et al.Repetitive tensile stress to rat caudal vertebrae inducing cartilage formation in the spinal ligaments:a possible role of mechanical stress in the development of ossification of the spinal ligaments[J].J Neurosurg Spine,2006,5(3):234-242.
[16] DONG AP,KIM SW,LEE SM,et al.Symptomatic myelopathy caused by ossification of the yellow ligament[J].Korean Journal of Spine,2012,9(4):348-351.
[17] LONG P,LIU F,PIESCO P,et al.Signaling by mechanical strain involves transcriptional regulation of proinflammatory genes in human periodontal ligament cells in vitro[J].Bone,2002,30(4):547-552.
[18] 卜宪敏,吴彬,徐芳芳,等.C(4/5)椎间不稳模型动物病理学变化及黄韧带转化生长因子β1的表达[J].中国组织工程研究,2015,19(18):2891-2895.
[19] 秦德安,张佐伦,李晓东,等.胸椎椎板倾斜角在胸椎黄韧带骨化中的解剖学意义[J].中国临床解剖学杂志,2006,24(6):634-636.
[20] 颜廷宾,张佐伦,于锡欣,等.胸椎黄韧带骨化与HLA-DQA1等位基因的相关性研究[J].中国矫形外科杂志,2002,10(14):50-52.
[21] KONG Q,MA X,LI F,et al.COL6A1 polymorphisms associated with ossification of the ligamentum flavum and ossification of the posterior longitudinal ligament[J].Spine(Phila Pa 1976),2007,32(25):2834-2838.
[22] MOBBS J,DVORAK M.Ossification of the ligamentum flavum:diet and genetics[J].J Clin Neurosci,2007,14(7):703-705.
[23] BRADDOCK R,SIMáN CM,HAMILTON K,et al.Gamma-linoleic acid and ascorbate improves skeletal ossification in offspring of diabetic rats[J].Pediatr Res,2002,51(5):647-652.
[24] 张亮,倪东馗,李立军,等.糖尿病对腰椎管狭窄症黄韧带骨化的影响[J].天津医科大学学报,2013,19(3):196-198.
[25] FAN DW,CHEN ZQ,CHEN YP,et al.Mechanistic roles of leptin in osteogenic stimulation in thoracic ligament flavum cells[J].J Biol Chem,2007,282(41):29958-29966.
[26] MüLLER W,FIRSCHING R,IFFLAND R.Age-related Calcium/Magnesium ratio in the ligamenta flava[J].Z Gerontol,1995,27(5):328-329.
[27] WANG Z,LI D,LI Q,et al.Changes in basic metabolic elements associated with the degeneration and ossification of ligamenta flava[J].J Spinal Cord Med,2008,31(3):279-284.
[28] MUTHUKUMAR N,KARUPPASWAMY U.Tumoral Calcium pyrophosphate dihydrate deposition disease of the ligamentum flavum[J].Neurosurgery,2003,53(1):103-108.
[29] 伊广坤,刘丽,李咸周.过量氟化物致腰椎黄韧带的退变与骨化[J].中国组织工程研究,2015,19(33):5301-5305.
[30] NISHIMURA R,HATA K,MATSUBARA T,et al.Regulation of bone and cartilage development by network between BMP signalling and transcription factors[J].J Biochem,2012,151(3):247-254.
[31] CHOKSHI FH,QUENCER RM,SMOKER WT.The “thickened”ligamentum flavum:is it buckling or enlargement?[J].AJNR Am J Neuroradiol,2010,31(10):1813-1816.
[32] ABBAS J,HAMOUD K,MASHARAWI M,et al.Ligamentum flavum thickness in normal and stenotic lumbar spines[J].Spine(Phila Pa 1976),2010,35(12):1225-1230.
[33] ALBRO MB,CIGAN AD,NIMS RJ,et al.Shearing of synovial fluid activates latent TGF-β[J].Osteoarthritis and Cartilage,2012,20(11):1374-1382.
[34] 张颖哲,吴东进,彭长亮,等.siRNA抑制转化生长因子-β1对小鼠黄韧带骨化的影响[J].山东大学学报(医学版),2014,52(8):27-33.
[35] 张慧,王贵超,韩兴龙,等.去分化间充质干细胞成骨再分化潜能的实验研究[J].南京医科大学学报(自然科学版),2013,33(8):1044-1048.
[36] RISBUD V,SHAPIRO M.Role of cytokines in intervertebral disc degeneration:pain and disc content[J].Nat Rev Rheumatol,2014,10(1):44-56.
[37] PARK OH,LEE HO,KANG MI,et al.Inflammatory cytokines induce fibrosis and ossification of human ligamentum flavum cells[J].J Spinal Disord Tech,2013,26(1):6-12.
[38] RANGASWAMI H,BULBULE A,KUNDU C.Osteopontin:role in cell signaling and cancer progression[J].Trends Cell Biol,2006,16(2):79-87.
[39] HOLM E,GLEBERZON JS,LIAO Y,et al.Osteopontin mediates mineralization and not osteogenic cell development in vitro[J].Biochem J,2014,464(3):355-364.
[40] CHEN Q,SHOU P,ZHANG LY,et al.An osteopontin-integrin interaction plays a critical role in directing adipogenesis and osteogenesis by mesenchymal stem cells[J].Stem Cells,2014,32(2):327-337.
[41] LAKEMEIER S,SCHMID R,FOLTZ L,et al.Increased expression of CD44 in hypertrophied ligamentum flavum and relevance of splice variants CD44v5 and CD44v6[J].Acta Neurochir(Wien),2012,154(2):359-365.
[42] 王哲,王全平,张俊华,等.骨形成蛋白在黄韧带骨化中的表达定位[J].第四军医大学学报,2002,23(4):341-343.
[43] YAYAMA T,UCHIDA K,KOBAYASHI S,et al.Thoracic ossification of the human ligamentum flavum:histopathological and immunohistochemical findings around the ossified lesion[J].J Neurosurg Spine,2007,7(2):184-193.
[44] KANG M,SUK S,LEE H,et al.Herniated intervertebral disk induces hypertrophy and ossification of ligamentum flavum[J].J Spinal Disord Tech,2014,27(7):382-389.