[1]赫军,李丽华,诸葛天瑜,等.综合疗法治疗强直性脊柱炎髋关节滑膜炎临床探析[J].中医正骨,2013,25(08):10-12.
　Jun*,Li Lihua,Zhuge Tianyu,et al.Clinical analysis of comprehensive therapy on synovitis of hip secondary to ankylosing spondylitis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2013,25(08):10-12.
点击复制

综合疗法治疗强直性脊柱炎髋关节滑膜炎临床探析()
分享到：

《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第25卷
期数:
2013年08期
页码:
10-12
栏目:
临床研究
出版日期:
2013-08-30

文章信息/Info

Title:
Clinical analysis of comprehensive therapy on synovitis of hip secondary to ankylosing spondylitis
作者:
赫军1; 李丽华2; 诸葛天瑜1; 孙捷1; 汤志刚1; 赫辉2
1.浙江省台州市博爱医院,浙江 台州 318050;
2.河南风湿病医院,河南 郑州 450045
Author(s):
Jun*; Li Lihua; Zhuge Tianyu; Sun Jie; Tang Zhigang; He Hui.*
Boai Hospital of Taizhou City,Taizhou 318050,Zhejiang,China
关键词:
强直性脊柱炎 滑囊炎 髋关节 中医药治疗 臭氧
Keywords:
Ankylosing spondylitis;  Synovitis; hip joint;  Traditional Chinese medicine therapy;  Ozone
摘要:
目的:观察采用中医药辨证内服,结合髋关节局部注射臭氧及患髋下肢牵引和关节功能锻炼等综合疗法治疗AS髋关节滑膜炎的临床疗效。方法:将60例经临床及影像学证实滑膜炎AS住院患者,随机分治疗组与对照组,每组30例,治疗组给予中药辨证内服,髋关节局部注射臭氧,下肢牵引,关节功能锻炼等综合疗法治疗,对照组给予柳氮磺胺吡啶片,美乐昔康片治疗,共治疗6周。治疗后观察对比2组患者的Harris评分,临床疗效及不良反应情况。结果:①Harris评分:治疗前2组患者Harris评分比较,差异无统计学意义(t=0.936,P=0.312); 治疗后2组患者Harris评分均改善,治疗组高于对照组(t=5.216,P=0.001)。②临床疗效:治疗后2组患者的症状体征均改善,治疗组临床疗效优于对照组(χ2=0.312,P=0.000)。③不良反应:治疗期间2组患者均未出现过敏反应。治疗组4例患者出现便溏,大便每日2次,心率加快2例; 对照组3例患者出现恶心,2例患者轻度肝功能受损。经对症处理后,2组患者不良反应均消失。2组患者不良反应发生率比较,差异无统计学意义(χ2=0.100,P=0.725)。结论:中医药辨证内服,结合髋关节局部注射臭氧及患髋下肢牵引和关节功能锻炼等综合疗法能改善AS髋关节滑膜炎临床症状体征及关节功能,且无严重不良反应,具有临床应用价值。
Abstract:
Objective:To observe the clinical efficacy of oral administration of traditional Chinese medicine(TCM)combined with local injection of ozone in hip joint,lower limb traction,functional exercise in the treatment of hip synovitis secondary to ankylosing spondylitis(AS).Method:60 hospitalized patients with synovitis secondary to AS confirmed clinically and radiographically were randomly divided into treatment group and control group with 30 cases in each group,the treatment group was given Chinese traditional medicine taken orally,local injection of ozone in hip joint,lower limb traction and joint functional exercise for six weeks.The control group was given Sulfasalazine tablets and Miller piroxicam tablets for six weeks.The harris hip scores,clinical efficacy and adverse reaction were compared between the two groups after treatment.Result:①Harris hip score:There was no significant difference in Harris hip score between the groups before treatment(t=0.936,P=0.312 ); the harris hip score of treatment group was higher than that of control group(t=5.216,P=0.001)after treatment.②The clinical efficacy:The symptoms and signs after treatment in both groups were improved,the effect in treatment group was superior to that in the control group(χ2=0.312,P=0.000).③Adverse reaction:No allergic reaction was observed during treatment in both groups.Loose stool with 2 times a day appeared in 4 cases of the treatment group,rapid heart rate appeared in 2 cases; 3 cases of the control group patients showed nausea,2 cases of patients with mild liver function damage.After proper treatment adverse reaction disappeared in the two groups.There was no significant difference in incidence of adverse reaction between the two groups(χ2=0.100,P=0.725).Conclusion:Oral administration of TCM combined with local injection of ozone in the hip,lower limb traction,joint function exercise could improve the clinical symptoms and function of joint of the AS hip synovitis,and with no serious adverse reaction,is of great value in clinical application.

参考文献/References:

[1] 张乃铮.临床风湿病学[M].上海:上海科学出版社,1999:155-157.
[2] 袁国华,郭军华,施桂英,等.强直性脊柱炎髋关节病变的危险因素[J].中华风湿病学杂志,1998,4(2):1892-1894.
[3] 白人骁,毕晓阳,张福江,等.关节成形术治疗强直性脊柱炎晚期严重髋关节畸形[J].中华骨科杂志,1999,19(7):400-404.
[4] 赫军,李丽华,汤志刚,等.中医综合治疗强直性脊柱炎83例[J].江苏中医药,2011,12(43):31.
[5] 徐凤和,刘传圣,张 维,等.医用臭氧治疗强直性脊柱炎的临床观察[J].中国疼痛医学杂志,2010,16(5):315.
[6] 蒋军辉,姜清田,苗志堃,等.注射臭氧治疗强直性脊柱炎所致髋痛172例[J].中国中医骨伤科杂志,2010,12(18):47.

备注/Memo

备注/Memo:
2013-02-22收稿 2013-07-04修回
更新日期/Last Update: 2013-08-30