[1]陈志伟,石关桐,钱晓忠.膝骨关节炎与软骨寡聚基质蛋白的相关性研究进展[J].中医正骨,2012,24(12):33-35.
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膝骨关节炎与软骨寡聚基质蛋白的相关性研究进展()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第24卷
期数:
2012年12期
页码:
33-35
栏目:
综述
出版日期:
2012-12-20

文章信息/Info

作者:
陈志伟石关桐钱晓忠
上海中医药大学附属曙光医院宝山分院,上海 201900
关键词:
骨关节炎膝 软骨寡聚基质蛋白 综述
摘要:
膝骨关节炎是一种慢性、进行性骨关节病,以关节软骨进行性退变与破坏、关节软骨再修复、软骨下骨重塑与硬化、骨赘形成及滑膜和关节腔的一系列生化及形态学改变为主要特征,其发病机制目前仍不清楚。软骨寡聚基质蛋白作为潜在的生物学标记物应用于膝骨关节炎的临床诊断具有广泛的应用前景,但目前其特异性和敏感性还缺少相应的循证医学证据。本文对近年来膝骨关节炎、软骨寡聚基质蛋白及二者的相关性的研究进展进行了综述。

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备注/Memo

备注/Memo:
通讯作者:石关桐 E-mail:gtshi@sina.com
更新日期/Last Update: 2012-12-20