[1]陈墨川,鲁光钱,陈颖异,等.加味阳和汤对绝经后骨质疏松症肾阳虚证患者骨密度的影响[J].中医正骨,2012,24(08):12-14.
 CHEN Mo-chuan*,LU Guang-qian,CHEN Ying-yi,et al.The influence to bone density of Jiaweiyanghe soup treatment of postmenopausal osteoporosis patients with insufficiency of kidney[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2012,24(08):12-14.
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加味阳和汤对绝经后骨质疏松症肾阳虚证患者骨密度的 影响()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第24卷
期数:
2012年08期
页码:
12-14
栏目:
临床研究
出版日期:
2012-08-20

文章信息/Info

Title:
The influence to bone density of Jiaweiyanghe soup treatment of postmenopausal osteoporosis patients with insufficiency of kidney
作者:
陈墨川1鲁光钱2陈颖异2黄建华2
1.大连医科大学,辽宁 大连 116044;
2.浙江省瑞安市人民医院,浙江 瑞安 325200
Author(s):
CHEN Mo-chuan*LU Guang-qianCHEN Ying-yiHUANG Jian-hua.
*Dalian Medical University of Liaoning Province,Dalian 116044,Liaoning,China
关键词:
骨质疏松症绝经后 肾阳虚证 骨密度 加味阳和汤
Keywords:
Chinese medicine therapy/Jiaweiyanghe soup Postmenopausal osteoporosis kidney yangxu Bone mineral density Clinical research
摘要:
目的:观察加味阳和汤对治疗绝经后骨质疏松症肾阳虚证患者骨密度的影响。方法:将81例绝经后骨质疏松症肾阳虚证患者随机分为两组,治疗组49例,应用自拟加味阳和汤治疗; 对照组32例,给仙灵骨葆胶囊口服。均经6个月治疗,观察两组临床疗效、治疗前后骨密度变化。结果:治疗组和对照组治疗后主要症状或体征的疗效有效率分别为有效率分别为87.76%和62.50%(P<0.05)。骨密度T值示治疗组与对照组治疗后比较P<0.05; 治疗组治疗前后比较P<0.05; 对照组治疗前后比较P>0.05。结论:加味阳和汤治疗绝经后骨质疏松症肾阳虚证可能机制是抑制了破骨细胞的产生和骨的吸收,促进了骨形成,改变绝经后的高转换状态,从而提高骨密度,达到了治疗绝经后骨质疏松症的治疗效果,是防治骨质疏松症的有效方法。
Abstract:
Objective:To observe the influence to bone density of Jiaweiyanghe soup treatment of postmenopausal osteoporosis patients with kidney yangxu.Methods:81 cases were randomly divided into the treatment group(49 cases)and the control group(32 cases),the treatment group were administrate with Jiaweiyanghe soup and the control group use Xianlinggubao capsule.Both by 6 months of therapy,observe curative effect of the two sets,bone mineral density before and after treatment.Results:The two groups after treatment,the main symptoms or signs the curative effect of the effective rate was efficient to 87.76% and 62.50%,respectively(P<0.05).The two groups after treatment,the bone mineral density T value is P<0.05; Before and after treatment the treatment group is P<0.05; before and after treatment the control group is P>0.05.Conclusion:The possible mechanism of Jiaweiyanghe soup in treatment of postmenopausal osteoporosis patients with kidney yangxu is to keep the broken bone cells and the formation of the bone absorption,promote the bone formation,change the high transition state,so as to improve the bone mineral density,to achieve the treatment effect,it is an effective method to prevent and treat osteoporosis.

参考文献/References:

[1] 王博,李玉雄.抗骨疏胶囊治疗原发性骨质疏松症的临床研究[J].中医正骨,2010,22(5):21-22.
[2] 刘忠厚,杨定桌,朱汉民,等.中国人原发性骨质疏松症诊断标准(试行)[J].中国骨质疏松杂志,1999,5(1):1-3.
[3] 郑筱萸,任德权,曹文庄,等.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:356-360.
[4] 郭振球,朱文,张瑞麟,等.中医诊断学[M].长沙:湖南科学技术出版社,1995:129.
[5] 杨少辉,吴素芳,许红霞.骨质疏松防治药物的研究进展[J].中国骨质疏松杂志,2010,16(10):786-790.
[6] 林志炜,陈益忠.中西医结合治疗老年性骨质疏松症[J].中国医药报,2008,5(11):112-113.
[7] 王志超,李志毅.鹿角胶丸对骨质疏松模型大鼠影响的实验研究[J].中医正骨,2003,15(11):16-17.
[8] 李全,王立新,卢坚.二仙提取液对去卵巢大鼠胫骨中段皮质骨形态计量学的影响[J].湖南中医药大学学报,2007,27(3):25-28.
[9] 相湘.熟地抗疲劳作用的实验研究[J].中国现代药物应用,2011,5(5):118-119.

更新日期/Last Update: 2012-08-20