[1]李大刚,苏培基,陈敢峰,等.中医药治疗骨质疏松性椎体压缩骨折的系统评价[J].中医正骨,2012,24(07):23-26.
　LI Da-gang*,SU Pei-ji,CHEN Gan-feng,et al.Systematic review on the curative effect of traditional Chinese medicine in the treatment of osteoporotic vertebral compression fractures[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2012,24(07):23-26.
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中医药治疗骨质疏松性椎体压缩骨折的系统评价()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第24卷
期数:
2012年07期
页码:
23-26
栏目:
文献研究
出版日期:
2012-07-30

文章信息/Info

Title:
Systematic review on the curative effect of traditional Chinese medicine in the treatment of osteoporotic vertebral compression fractures
作者:
李大刚; 苏培基; 陈敢峰; 陈世忠; 高恒
广州中医药大学附属中山中医院,广东 中山 528401
Author(s):
LI Da-gang*; SU Pei-ji; CHEN Gan-feng; CHEN Shi-zhong; GAO Heng.*
Hospital of traditional Chinese medicine of Zhongshan,Zhongshan 528401,Guangdong,China
关键词:
骨质疏松 脊柱骨折 骨折; 压缩性 中医疗法 中药疗法 Meta分析
Keywords:
Osteoporosis;  Spinal fractures;  Fractures;  compression;  TCM therapy;  Drug therapy(TCD);  Meta-analysis
摘要:
目的:评价中医药治疗骨质疏松性椎体压缩骨折的临床疗效。方法:以“压缩性骨折”“椎体骨折”“腰椎骨折”“胸椎 骨折”4个关键词与“中医疗法”“中药疗法”及“中医药疗法”3个关键词的任意组合为关键词,用计算机检索中国知网、万方 数据库、维普数据库1999年1月至2011年11月期间收录的所有中医药治疗骨质疏松性椎体压缩骨折的随机对照研究文献。利用 Cochrane协作网提供的Revman5.1统计软件进行统计分析。结果:共检索出文献483篇,通过筛选最终共纳入11篇文献,涉及953例 患者。在骨密度方面,治疗组优于对照组(Z=2.830,P=0.005),漏斗图对称,提示存在发表偏倚的可能性较小; 在功能改善方面,治 疗组显效率高于对照组(Z=2.580,P=0.010),敏感性分析显示,前后结果没有本质改变; 有效率比较,治疗组与对照组的差异无统 计学意义(Z=0.740,P=0.460)。结论:中医药治疗可明显改善骨质疏松性椎体压缩骨折患者的脊柱功能,提高骨密度,是治疗骨质 疏松性椎体压缩骨折的重要方法。
Abstract:
Objective:To evaluate the clinical curative effect of traditional Chinese medicine in the treatment of osteoporotic vertebral compression fractures(OVCF).Methods:All the literatures of randomized controlled trial for traditional Chinese medicine in OVCF treatment included from January 1999 to November 2011 were retrieved from China national knowledge internet,Wanfang Database and Vip Database through computer,and any combination words from the 4 keywords as Compression fracture,Vertebral fracture,Lumbar vertebrae fracture,Thoracic vertebrae fracture and from the 3 keywords as Traditional Chinese medicine(TCM)therapy,Traditional Chinese Drug(TCD)therapy,TCM and TCD therapy were selected as index terms.Statistical analysis was carried on through Revman5.1 software provided by Cochrane collaboration networks.Results:Four hundred and eighty-three literatures in total were retrieved.After selection,11 literatures including 953 patients met the inclusion criteria finally.Bone mineral density(BMD)of treatment group was better than that of control group (Z=2.830,P=0.005),and the symmetrical funnel plot demonstrated that the possibility of existing publication bias was small.On the aspect of the function of knee joint,the excellence rate of treatment group was higher than that of control group(Z=2.580,P=0.010),and the result of sensitivity analysis indicated that there was not essential change in the results before and after the treatment.There was not statistical difference in effective rate between the 2 groups(Z=0.740,P=0.460).Conclusion:Traditional Chinese medicine therapy can obviously improve the spinal function and BMD of OVCF patients,therefore,it is an important method in OVCF treatment.

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相似文献/References:

[1]顾伯龙.骨质疏松和椎体转移瘤所致单个椎体压缩骨折的MRI鉴别诊断[J].中医正骨,2012,24(12):30.

备注/Memo

备注/Memo:
2012-03-04收稿 2012-04-12修回
更新日期/Last Update: 2012-07-30