[1]蓝相洲,李铃佳,唐燕,等.数字健康技术辅助的康复疗法治疗膝骨关节炎效果的Meta分析[J].中医正骨,2025,37(12):21-26,31.
　LAN Xiangzhou,LI Lingjia,TANG Yan,et al.Efficacy of digital health technology-assisted rehabilitation therapy for treatment of knee osteoarthritis:a meta-analysis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2025,37(12):21-26,31.
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数字健康技术辅助的康复疗法治疗膝骨关节炎效果的Meta分析()

《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第37卷
期数:
2025年12期
页码:
21-26,31
栏目:
文献研究
出版日期:
2025-12-20

文章信息/Info

Title:
Efficacy of digital health technology-assisted rehabilitation therapy for treatment of knee osteoarthritis:a meta-analysis
作者:
蓝相洲1; 李铃佳2; 唐燕3; 贾庆2; 何芳颐2; 邝高艳1; 陈青1; 郭城1
(1.湖南中医药大学第一附属医院,湖南 长沙 410007; 2.湖南中医药大学护理学院,湖南 长沙 410208; 3.湖南中医药大学第二附属医院,湖南 长沙 410005)
Author(s):
LAN Xiangzhou1; LI Lingjia2; TANG Yan3; JIA Qing2; HE Fangyi2; KUANG Gaoyan1; CHEN Qing1; GUO Cheng1
1.The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410007,Hunan,China 2.School of Nursing,Hunan University of Chinese Medicine,Changsha 410208,Hunan,China 3.The Second Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410005,Hunan,China
关键词:
骨关节炎; 膝;  数字健康;  康复;  专题Meta分析
Keywords:
osteoarthritis; knee;  digital health;  rehabilitation;  meta-analysis as topic
摘要:
目的:系统评价数字健康技术(digital health technology,DHT)辅助的康复疗法治疗膝骨关节炎(knee osteoarthritis,KOA)的效果。方法:检索中国知网、万方数据库、维普网、中国生物医学文献服务系统、PubMed、Embase、Web of Science、Cochrane Library中比较DHT辅助的康复疗法和常规康复疗法治疗KOA临床疗效的随机对照试验,检索时限均为建库至2025年1月。由2名研究人员独立筛选文献、提取数据并评价纳入研究的偏倚风险后,采用R4.4.1软件的Meta程序包进行Meta分析。结果:共纳入17项研究,涉及1049例KOA患者,其中包括普通KOA患者和已行膝关节置换术(total knee arthroplasty,TKA)的KOA患者。Meta分析结果显示,与常规康复疗法相比,DHT辅助的康复疗法可显著降低患者的膝关节疼痛数字分级量表评分[TKA患者:SMD=-0.71,95%CI(-1.31,-0.12),P=0.018; 普通KOA患者:SMD=-0.60,95%CI(-0.77,-0.42),P=0.000]及西安大略和麦克马斯特大学骨关节炎指数评分[TKA患者:SMD=-0.55,95%CI(-1.08,-0.01),P=0.047; 普通KOA患者:SMD=-1.19,95%CI(-2.17,-0.21),P=0.017]; DHT辅助的康复疗法改善已行TKA的KOA患者站立行走时间的效果优于常规康复疗法[SMD=-0.60,95%CI(-1.17,-0.04),P=0.037],2种疗法改善普通KOA患者站立行走时间的差异无统计学意义[SMD=-0.10,95%CI(-0.39,0.20),P=0.513]; 2种疗法改善已行TKA的KOA患者膝关节活动度的差异无统计学意义[SMD=0.46,95%CI(-0.02,0.93),P=0.061],针对普通KOA患者的研究仅1项,未进行合并分析。Egger's检验结果提示不存在发表偏倚(P=0.078)。结论:现有证据表明,对于KOA患者,DHT辅助的康复疗法在减轻膝关节疼痛症状、改善膝关节功能方面的效果优于常规康复疗法。
Abstract:
Objective:To systematically review the therapeutic efficacy of digital health technology(DHT)-assisted rehabilitation therapy in treatment of knee osteoarthritis(KOA).Methods:All the randomized controlled trial(RCT)articles about the clinical outcomes of DHT-assisted rehabilitation therapy versus conventional rehabilitation therapy for treatment of KOA included from database's inception to January 2025 were retrieved from the China National Knowledge Infrastructure,Wanfang Database,Vip Database,Chinese Biomedical Literature Service System,PubMed,Embase,Web of Science and Cochrane Library.The pertinent articles were screened,the information was extracted and the risk of bias of the included researches in the articles was assessed independently by two researchers,and then a Meta-analysis was conducted using the Meta package in R software(version 4.4.1).Results:Seventeen articles(1049 KOA patients)were included in the final analysis,comprising both general KOA patients and post-total knee arthroplasty(TKA)KOA patients.The meta-analysis revealed that,compared to the conventional rehabilitation therapy,the DHT-assisted rehabilitation therapy significantly reduced patient's knee pain numerical rating scale(NRS)score and Western Ontario and McMaster Universities osteoarthritis index(WOMAC)score(TKA patients:SMD=-0.71,95%CI(-1.31,-0.12),P=0.018; general KOA patients:SMD=-0.60,95%CI(-0.77,-0.42),P=0.000; TKA patients:SMD=-0.55,95%CI(-1.08,-0.01),P=0.047; general KOA patients:SMD=-1.19,95%CI(-2.17,-0.21),P=0.017).Furthermore,the DHT-assisted rehabilitation therapy demonstrated superior efficacy in reducing timed up-and-go test duration compared to the conventional rehabilitation therapy in post-TKA KOA patients(SMD=-0.60,95%CI(-1.17,-0.04),P=0.037),while,the two therapies are comparable in improving this outcome in general KOA patients(SMD=-0.10,95%CI(-0.39,0.20),P=0.513).Moreover,the two therapies showed comparable therapeutic effect in improving knee range of motion in post-TKA KOA patients(SMD=0.46,95%CI(-0.02,0.93),P=0.061),while,only one study focused on general KOA patients,so no pooled analysis was conducted.The publication bias was analyzed based on the knee pain NRS score,and the result of Egger's test showed that there was no publication bias in the included articles(P=0.078).Conclusion:Available evidences suggest that the DHT-assisted rehabilitation therapy is superior to the conventional rehabilitation therapy in alleviating knee pain and improving knee function in KOA patients.

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备注/Memo

备注/Memo:
基金项目:国家中医优势专科(护理学)建设项目(国中医药医政函〔2024〕90号); 湖南省自然科学基金项目(2024JJ9424); 湖南省科技创新计划项目(2024RC3203); 湖南中医药大学校院联合重点项目(2023XYLH008)
通讯作者:郭城 E-mail:2652561774@qq.com
(收稿日期:2025-06-30 本文编辑:李晓乐)
更新日期/Last Update: 2025-12-20