[1]陆晔庆,高明,沈洁,等.针刺联合牵引治疗神经根型颈椎病[J].中医正骨,2025,37(10):66-68.
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针刺联合牵引治疗神经根型颈椎病()

《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第37卷
期数:
2025年10期
页码:
66-68
栏目:
临床报道
出版日期:
2025-10-20

文章信息/Info

作者:
陆晔庆1; 高明1; 沈洁2; 蒉潇飞1; 黄佳颖1
1.上海中医药大学针灸推拿学院,上海 201203; 2.上海中医药大学附属上海市中西医结合医院,上海 200082
关键词:
颈椎病;  神经根病;  针刺疗法;  牵引术
摘要:
目的:观察针刺联合牵引治疗神经根型颈椎病(cervical spondylotic radiculopathy, CSR)的临床疗效,并初步探讨其作用机制。方法:2024年1月至2025年1月,采用针刺联合牵引治疗CSR患者51例。男32例,女19例。年龄18～65岁,中位数 37岁。病程6个月至5年,中位数2.5年。所有患者均接受为期8周的针刺联合牵引治疗,期间均口服甲钴胺片。采用颈椎功能障碍指数(neck disability index,NDI)评分评价颈椎功能,采用疼痛视觉模拟量表(visual analogue scale,VAS)评分评价颈部疼痛程度,并测定血清白细胞介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、腺苷一磷酸活化的蛋白质激酶(adenosine monophosphate-activated protein kinase,AMPK)、沉默信息调节因子1(silence information regulator 1,SIRT1)、核因子κB(nuclear factor-κB,NF-κB)水平。治疗8周后评价综合疗效。结果:与治疗前相比,治疗4周和8周后患者的NDI评分与颈部疼痛VAS评分均呈降低趋势(F=170.946,P=0.000; F=263.112,P=0.000)。治疗8周后,患者的血清IL-6、TNF-α、NF-κB水平均较治疗前下降(t=18.382,P=0.000; t=26.843,P=0.000; t=11.323,P=0.000),AMPK和SIRT1水平均较治疗前升高(t=16.324,P=0.000; t=11.907,P=0.000)。治疗8周后评价综合疗效,治愈19例、显效17例、有效12例、无效 3例。结论:针刺联合牵引治疗CSR,可有效缓解疼痛、改善颈椎功能,总体疗效良好。其作用机制可能与上调AMPK、SIRT1表达并抑制NF-κB活性,从而下调IL-6与TNF-α表达有关。

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备注/Memo

备注/Memo:
通讯作者:高明 E-mail:gaoming688@sina.com
更新日期/Last Update: 1900-01-01