参考文献/References:
[1] MCCORMICK J R,SAMA A J,SCHILLER N C,et al.Cervical spondylotic myelopathy:a guide to diagnosis and management[J].J Am Board Fam Med,2020,33(2):303-313.
[2] DONNALLY C J 3rd,PATEL P D,CANSECO J A,et al.Current management of cervical spondylotic myelopathy[J].Clin Spine Surg,2022,35(1):E68-E76.
[3] 段寒,谭洪宇,张杨,等.颈椎曲度与脊髓型颈椎病的关系研究[J].中医正骨,2022,34(1):8-12.
[4] KADAÑKA Z,BEDNARÍK J,NOVOTNY O,et al.Cervical spondylotic myelopathy:conservative versus surgical treatment after 10 years[J].Eur Spine J,2011,20(9):1533-1538.
[5] 陈印磊,夏建龙,蔡平.中医对脊髓型颈椎病的认识及治疗进展[J].中医药临床杂志,2018,30(10):1957-1961.
[6] 禚汉杰,周英杰,王少纯,等.从“督”论治脊髓型颈椎病[J].中国中医骨伤科杂志,2018,26(2):57-60.
[7] 睦顺姬,叶秀兰,姚敏,等.中医药治疗脊髓型颈椎病的机理研究概况[J].世界中医药,2017,12(1):222-224.
[8] 莫文,王拥军,吴弢,等.施杞运用中医药治疗颈椎病的经验[J].上海中医药杂志,2017,51(11):1-5.
[9] 陆洋,谢林.基于“肾主骨生髓”辨治脊髓型颈椎病的经验[J].上海中医药杂志,2019,53(12):30-32.
[10] 中国中西医结合学会骨伤科分会,莫文,袁文.脊髓型颈椎病中西医结合诊疗专家共识[J].中国骨伤,2022,35(8):790-798.
[11] 文天林,孙天胜.脊髓型颈椎病的病理演变和治疗研究进展[J].人民军医,2017,60(1):75-76.
[12] MORISHITA Y,FALAKASSA J,NAITO M,et al.The kinematic relationships of the upper cervical spine[J].Spine(Phila Pa 1976),2009,34(24):2642-2645.
[13] DOPPMAN J L.The mechanism of ischemia in anteropos-terior compression of the spinal cord[J].Invest Radiol,1975,10(6):543-551.
[14] 陈锋,施杞,韦贵康,等.脊髓型颈椎病脊髓微循环改变及中药效应观察[J].中医正骨,2004,16(10):3-4.
[15] 唐彬,朱立国,陈忻,等.益肾养髓方对脊髓型颈椎病大鼠受损脊髓微血管再生的影响[J].中国中医药信息杂志,2022,29(5):51-55.
[16] 陈锋,黄有荣,崔伟,等.活血方对脊髓型颈椎病脊髓微循环的影响[J].广西中医药,2014,37(3):75-77.
[17] 王羽丰.补肾活血方治疗脊髓型颈椎病疗效及与内皮素关系的研究[D].广州:广州中医药大学,2002.
[18] 曲安龙.益肾通络汤对脊髓型颈椎病患者ET表达水平的影响及疗效观察[J].陕西中医,2017,38(5):601-602.
[19] 欧传双.补气通络法对脊髓型颈椎病术后Aβ蛋白、血浆内皮素、一氧化氮表达的影响[D].广州:广州中医药大学,2017.
[20] 李志强,袁尚荣,陈泽斌.三七总皂甙对大鼠脊髓损伤后一氧化氮合酶表达的影响[J].中国脊柱脊髓杂志,2001,11(4):197-198.
[21] 周思启.脊髓型颈椎病患者颈椎间盘IL-1β、IL-6、IL-8和TNF-α水平与JOA评分的相关性研究[D].合肥:安徽医科大学,2007.
[22] 王洪流,董又坤,廖志刚,等.花椒毒酚对大鼠脊髓型颈椎病的治疗作用及机制[J].新乡医学院学报,2021,38(10):917-923.
[23] 周龙云.参芪麝蓉丸抑制线粒体过度分裂干预脊髓型颈椎病神经炎症反应的机制研究[D].上海:上海中医药大学,2020.
[24] 杨家祥,杨环玮,董军格,等.丹红提取物对脊髓型颈椎病的治疗机制初探[J].中国医科大学学报,2017,46(8):710-712.
[25] 丁海霞,樊成虎,王玉泉,等.黄芪总苷对脊髓型颈椎病大鼠模型椎间盘细胞因子IL-6、TNF-α的影响[J].西部中医药,2017,30(7):20-25.
[26] 唐占英,王拥军,胡志俊,等.益气化瘀补肾方对压迫和减压后大鼠背根节神经元PLA2、PGE2表达影响[J].四川中医,2012,30(9):36-39.
[27] 杨宇.益气活血方治疗大鼠脊髓型颈椎病的实验研究[D].南京:南京中医药大学,2016.
[28] ASHOK A,ANDRABI S S,MANSOOR S,et al.Antioxidant therapy in oxidative stress-induced neurodegenerative diseases:role of nanoparticle-based drug delivery systems in clinical translation[J].Antioxidants(Basel),2022,11(2):408.
[29] KANG Y,LI Q,ZHU R,et al.Identification of ferroptotic genes in spinal cord injury at different time points:bioinformatics and experimental validation[J].Mol Neurobiol,2022,59(9):5766-5784.
[30] ANJUM A,YAZID M D,FAUZI DAUD M,et al.Spinal cord injury:pathophysiology,multimolecular interactions,and underlying recovery mechanisms[J].Int J Mol Sci,2020,21(20):7533.
[31] WILSON J X,GELB A W.Free radicals,antioxidants,and neurologic injury:possible relationship to cerebral protection by anesthetics[J].J Neurosurg Anesthesiol,2002,14(1):66-79.
[32] CHEN Y,ZHANG J,LIN Y,et al.Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS[J].EMBO Rep,2011,12(6):534-541.
[33] 田子睿.参芪麝蓉丸治疗脊髓型颈椎病的机制研究[D].上海:上海中医药大学,2019.
[34] KLINEBERG E.Cervical spondylotic myelopathy:a review of the evidence[J].Orthop Clin North Am,2010,41(2):193-202.
[35] TRACY J A,BARTLESON J D.Cervical spondylotic mye-lopathy[J].Neurologist,2010,16(3):176-187.
[36] 韦贵康,陈锋,韦坚,等.中药“脊髓康”内服治疗脊髓型颈椎病32例临床观察与实验研究[J].广西中医学院学报,2001,4(4):86-88.
[37] CHEN D F,SCHNEIDER G E,MARTINOU J C,et al.Bcl-2 promotes regeneration of severed axons in mammalian CNS[J].Nature,1997,385(6615):434-439.
[38] 徐远坤.“健身丹”对脊髓型颈椎病神经细胞凋亡相关基因表达影响的研究[D].贵阳:贵阳中医学院,2007.
[39] GAUDET A D,FONKEN L K.Glial cells shape pathology and repair after spinal cord injury[J].Neurotherapeutics,2018,15(3):554-577.
[40] 秦晓宽,银河,杨博文,等.益肾养髓方对脊髓型颈椎病大鼠脊髓中星形胶质细胞过度增殖的影响[J].中药新药与临床药理,2022,33(2):173-179.
[41] HERRMANN J E,IMURA T,SONG B,et al.STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury[J].Neurosci,2008,28(28):7231-7243.
[42] WANG Y,LAI X,WU D,et al.Umbilical mesenchymal stem cell-derived exosomes facilitate spinal cord functional recovery through the miR-199a-3p/145-5p-mediated NGF/TrkA signaling pathway in rats[J].Stem Cell Res Ther,2021,12(1):117.
[43] XU Z X,ZHANG L Q,ZHOU Y N,et al.Histological and functional outcomes in a rat model of hemisected spinal cord with sustained VEGF/NT-3 release from tissue-engineered grafts[J].Artif Cells Nanomed Biotechnol,2020,48(1):362-376.
中医正骨2023年12月第35卷第12期 J Trad Chin Orthop Trauma,2023,Vol.35,No.12(总921)
(总922)中医正骨2023年12月第35卷第12期 J Trad Chin Orthop Trauma,2023,Vol.35,No.12
[44] 唐彬,银河,杨博文,等.益肾养髓方对脊髓型颈椎病大鼠脊髓中神经营养因子表达的影响及其神经修复作用研究[J].中国全科医学,2021,24(35):4447-4456.
[45] 谢兴文,施杞,王拥军.益气化瘀补肾方对大鼠慢性脊髓损伤后影响的实验研究[J].上海中医药杂志,2009,43(8):61-63.
[46] LIANG H Z,LUO R J,LI G C,et al.The proteolysis of ECM in intervertebral disc degeneration[J].Int J Mol Sci,2022,23(3):1715.
[47] GREENE J,WANG M,LIU Y E,et a1.Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4[J].J Biol Chem,1996,271(48):30375-30380.
[48] 施杞,王拥军,李晨光,等.益气化瘀补肾方及拆方影响椎间盘细胞外基质胶原和代谢酶mRNA表达的研究[J].中国中西医结合杂志,2007,27(2):142-146.
[49] 李具宝,赵红云,赵永见,等.益气化瘀补肾方对退变椎间盘细胞蛋白聚糖和X型胶原mRNA表达的影响[J].中西医结合学报,2011,9(10):1138-1144.
[50] 赵飞,王其友.淫羊藿苷对大鼠腰椎间盘退变影响的实验研究[J].辽宁中医药大学学报,2015,17(10):36-38.
[51] 宋永嘉.参芪麝蓉丸调控BDNF/TrkB信号通路对大鼠颈髓双节段双侧慢性压迫模型神经功能恢复的研究[D].上海:上海中医药大学,2020.
[52] CHENG X,YU Z,XU J,et al.Pathophysiological changes and the role of Notch-1 activation after decompression in a compressive spinal cord injury rat model[J].Front Neurosci,2021,15:579431.
[53] 劳泽辉,凌国伟,华国花.circRNAs调控NF-κB信号通路在脊髓型颈椎病中的作用及机制研究[J].中国医学工程,2022,30(12):24-28.
[54] LIU H,ZHANG J,XU X,et al.SARM1 promotes neuroinflammation and inhibits neural regeneration after spinal cord injury through NF-κB signaling[J].Theranostics,2021,11(9):4187-4206.
[55] XU S,WANG J,JIANG J,et al.TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury[J].Cell Death Dis,2020,11(8):693.
[56] WANG X,FU Y,BOTCHWAY B O A,et al.Quercetin can improve spinal cord injury by regulating the mTOR signaling pathway[J].Front Neurol,2022,13:905640.
[57] WANG Y F,ZU J N,LI J,et al.Curcumin promotes the spinal cord repair via inhibition of glial scar formation and inflammation[J].Neurosci Lett,2014,560:51-56.
[58] MENG H Y,SHAO D C,LI H,et al.Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway[J].Mol Med Rep,2018,18(2):2237-2244.
[59] 敬聪,王志刚,王君,等.脊髓损伤相关信号通路在脊髓损伤修复过程中的研究进展[J].中国医药导报,2021,18(16):52-55.