参考文献/References:
[1] PITTENGER M F,MACKAY A M,BECK S C,et al.Multilineage potential of adult human mesenchymal stem cells[J].Science,1999,284(5411):143-147.
[2] KO J H,SETHI G,UM J Y,et al.The role of resveratrol in cancer therapy[J].Int J Mol Sci,2017,18(12):2589.
[3] RAUF A,IMRAN M,SULERIA H A R,et al.A comprehensive review of health perspectives of resveratrol[J].Food Funct,2017,8(12):4284-4305.
[4] POULSEN M M,FJELDBORG K,ORNSTRUP M J,et al.Resveratrol and inflammation:challenges in translating pre-clinical findings to improved patient outcomes[J].Biochim Biophys Acta,2015,1852(6):1124-1136.
[5] CARRIZZO A,FORTE M,DAMATO A,et al.Antioxidant effects of resveratrol in cardiovascular,cerebral and metabolic diseases[J].Food Chem Toxicol,2013,61:215-226.
[6] WANG Y J,ZHAO P,SUI B D,et al.Resveratrol enhances the functionality and improves the regeneration of mesenchymal stem cell aggregates[J].Exp Mol Med,2018,50(6):1-15.
[7] VAUZOUR D.Dietary polyphenols as modulators of brain functions:biological actions and molecular mechanisms underpinning their beneficial effects[J].Oxid Med Cell Longev,2012,2012(Special Issue):914273.
[8] BURNS J,YOKOTA T,ASHIHARA H,et al.Plant foods and herbal sources of resveratrol[J].J Agric Food Chem,2002,50(11):3337-3340.
[9] CAMONT L,COTTART C H,RHAYEM Y,et al.Simple spectrophotometric assessment of the trans-/cis-resveratrol ratio in aqueous solutions[J].Anal Chim Acta,2009,634(1):121-128.
[10] JOHNSON W D,MORRISSEY R L,USBORNE A L,et al.Subchronic oral toxicity and cardiovascular safety pharmacology studies of resveratrol,a naturally occurring polyphenol with cancer preventive activity[J].Food Chem Toxicol,2011,49(12):3319-3327.
[11] SERGIDES C,CHIRIL M,SILVESTRO L,et al.Bioavailability and safety study of resveratrol 500 mg tablets in healthy male and female volunteers[J].Exp Ther Med,2016,11(1):164-170.
[12] HUSSAIN S A,MAROUF B H,ALI Z S,et al.Efficacy and safety of co-administration of resveratrol with meloxicam in patients with knee osteoarthritis:a pilot interventional study[J].Clin Interv Aging,2018,13:1621-1630.
[13] SCHILLING T,EBERT R,RAAIJMAKERS N,et al.Effects of phytoestrogens and other plant-derived compounds on mesenchymal stem cells,bone maintenance and regeneration[J].J Steroid Biochem Mol Biol,2014,139:252-261.
[14] JUSTESEN J,STENDERUP K,EBBESEN E N,et al.Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis[J].Biogerontology,2001,2(3):165-171.
[15] PELTZ L,GOMEZ J,MARQUEZ M,et al.Resveratrol exerts dosage and duration dependent effect on human mesenchymal stem cell development[J].PLoS One,2012,7(5):e37162.
[16] CALDARELLI I,SPERANZA M C,BENCIVENGA D,et al.Resveratrol mimics insulin activity in the adipogenic commitment of human bone marrow mesenchymal stromal cells[J].Int J Biochem Cell Biol,2015,60:60-72.
[17] LI Y,D?MARK S,EDLUND U,et al.Resveratrol-conjugated poly-ε-caprolactone facilitates in vitro mineralization and in vivo bone regeneration[J].Acta Biomater,2011,7(2):751-758.
[18] WU G,WANG L,LI H,et al.Function of sustained released resveratrol on IL-1β-induced hBMSC MMP13 secretion inhibition and chondrogenic differentiation promotion[J].J Biomater Appl,2016,30(7):930-939.
[19] GENG Y W,ZHANG Z,LIU M Y,et al.Differentiation of human dental pulp stem cells into neuronal by resveratrol[J].Cell Biol Int,2017,41(12):1391-1398.
[20] HUANG J G,SHEN C B,WU W B,et al.Primary cilia mediate sonic hedgehog signaling to regulate neuronal-like differentiation of bone mesenchymal stem cells for resveratrol induction in vitro[J].J Neurosci Res,2014,92(5):587-596.
[21] JOE I S,JEONG S G,CHO G W.Resveratrol-induced SIRT1 activation promotes neuronal differentiation of human bone marrow mesenchymal stem cells[J].Neurosci Lett,2015,584:97-102.
[22] 黄玉圣,吕辰菲,庄景燊,等.细胞传代对SD大鼠骨髓间充质干细胞衰老的影响[J].中国老年学杂志,2019,39(9):2189-2192.
[23] LIAN J C,LV S J,LIU C,et al.Effects of serial passage on the characteristics and cardiac and neural differentiation of human umbilical cord Wharton’s jelly-derived mesenchymal stem cells[J].Stem Cells Int,2016,2016:9291013.
[24] WANG H,HU Z X,WU J,et al.SIRT1 promotes osteogenic differentiation and increases alveolar bone mass via bmi1 activation in mice[J].J Bone Miner Res,2019,34(6):1169-1181.
[25] CHOI S M,LEE K M,RYU S B,et al.Enhanced articular cartilage regeneration with SIRT1-activated MSCs using gelatin-based hydrogel[J].Cell Death Dis,2018,9(9):866.
[26] CORWIN W L,BAUST J M,BAUST J G,et al.Characterization and modulation of human mesenchymal stem cell stress pathway response following hypothermic storage[J].Cryobiology,2014,68(2):215-226.
[27] WANG X,MA S,MENG N,et al.Resveratrol exerts dosage-dependent effects on the self-renewal and neural differentiation of hUC-MSCs[J].Mol Cells,2016,39(5):418-425.
[28] ZHOU T,YAN Y R,ZHAO C C,et al.Resveratrol improves osteogenic differentiation of senescent bone mesenchymal stem cells through inhibiting endogenous reactive oxygen species production via AMPK activation[J].Redox Rep,2019,24(1):62-69.
[29] LV Y J,YANG Y,SUI B D,et al.Resveratrol counteracts bone loss via mitofilin-mediated osteogenic improvement of mesenchymal stem cells in senescence-accelerated mice[J].Theranostics,2018,8(9):2387-2406.
[30] YOON D S,CHOI Y,CHOI S M,et al.Different effects of resveratrol on early and late passage mesenchymal stem cells through β-catenin regulation[J].Biochem Biophys Res Commun,2015,467(4):1026-1032.
[31] VIDONI C,FERRARESI A,SECOMANDI E,et al.Autophagy drives osteogenic differentiation of human gingival mesenchymal stem cells[J].Cell Commun Signal,2019,17(1):98.
[32] SONG L H,PAN W,YU Y H,et al.Resveratrol prevents CsA inhibition of proliferation and osteoblastic differentiation of mouse bone marrow-derived mesenchymal stem cells through an ER/NO/cGMP pathway[J].Toxicol In Vitro,2006,20(6):915-922.
[33] B?KESJ?C M,LI Y,LINDGREN U,et al.Activation of SIRT1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells[J].Cells Tissues Organs,2006,21(7):993-1002.
[34] DAI Z,LI Y,QUARLES L D,et al.Resveratrol enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via ER-dependent ERK1/2 activation[J].Phytomedicine,2007,14(12):806-814.
[35] ZHAO X E,YANG Z S,ZHANG H,et al.Resveratrol promotes osteogenic differentiation of canine bone marrow mesenchymal stem cells through Wnt/Beta-Catenin signaling pathway[J].Cell Reprogram,2018,20(6):371-381.
[36] GAO X,GE J,LI W,et al.LncRNA KCNQ1OT1 promotes osteogenic differentiation to relieve osteolysis via Wnt/β-catenin activation[J].Cell Biosci,2018,8:19.
[37] SREEKUMAR V,ASPERA-WERZ R,EHNERT S,et al.Resveratrol protects primary cilia integrity of human mesenchymal stem cells from cigarette smoke to improve osteogenic differentiation in vitro[J].Arch Toxicol,2017,92(4):1525-1538.
[38] ZHOU Y Q,JIANG R,AN L Q,et al.Benzo[a]pyrene impedes self-renewal and differentiation of mesenchymal stem cells and influences fracture healing[J].Sci Total Environ,2017(587/588):305-315.
[39] SINGH S U,CASPER R F,FRITZ P C,et al.Inhibition of dioxin effects on bone formation in vitro by a newly described aryl hydrocarbon receptor antagonist,resveratrol[J].J Endocrinol,2000,167(1):183-195.
[40] CHEN X,LI M,YAN J K,et al.Alcohol induces cellular senescence and impairs osteogenic potential in bone marrow-derived mesenchymal stem cells[J].Alcohol Alcohol,2017,52(3):289-297.
[41] LI M,YAN J K,CHEN X,et al.Spontaneous up-regulation of SIRT1 during osteogenesis contributes to stem cells’ resistance to oxidative stress[J].J Cell Biochem,2018,119(6):4928-4944.
[42] LI J,XIN Z X,CAI M J.The role of resveratrol in bone marrow-derived mesenchymal stem cells from patients with osteoporosis[J].J Cell Biochem,2019,120(10):16634-16642.
[43] CHEN X H,SHI Z G,LIN H B,et al.Resveratrol alleviates osteoporosis through improving the osteogenic differentiation of bone marrow mesenchymal stem cells[J].Eur Rev Med Pharmacol Sci,2019,23(14):6352-6359.
[44] ORNSTRUP M J,HARSL?F T,S?RENSEN L,et al.Resveratrol increases osteoblast differentiation in vitro independently of inflammation[J].Calcif Tissue Int,2016,99(2):155-163.
[45] FENG G J,ZHENG K,SONG D H,et al.SIRT1 was involved in TNF-α-promoted osteogenic differentiation of human DPSCs through Wnt/β-catenin signal[J].In Vitro Cell Dev Biol Anim,2016,52(10):1001-1011.