[1]张建方,金国强,姚航军,等.补阳还五汤加减预防髋关节置换术后深静脉血栓形成的临床研究.[J].中医正骨,2013,25(02):19-21.
　ZHANG Jian-fang*,JIN Guo-qiang,YAO Hang-jun,et al.Bu Yang Huan Five Decoction on prevention of deep vein thrombosis after total hip arthroplasty[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2013,25(02):19-21.
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补阳还五汤加减预防髋关节置换术后深静脉血栓形成的 临床研究.()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第25卷
期数:
2013年02期
页码:
19-21
栏目:
临床研究
出版日期:
2013-02-20

文章信息/Info

Title:
Bu Yang Huan Five Decoction on prevention of deep vein thrombosis after total hip arthroplasty
作者:
张建方; 金国强; 姚航军; 朱保金
浙江省诸暨市中医院,浙江 诸暨 311800
Author(s):
ZHANG Jian-fang*; JIN Guo-qiang; YAO Hang-jun; ZHU Bao-jin.
*TCM Hospital of Zhuji City,Zhuji 311800,Zhejiang,China
关键词:
人工髋关节置换术 下肢深静脉血栓 补阳还五汤加减
Keywords:
Hip Arthroplasty;  Deep Vein Thrombosis Of Lower Extremity;  Buyang Huanwu Decoction
摘要:
目的:观察补阳还五汤加减方预防髋关节置换术后深静脉血栓形成的疗效。方法:将收治的77例病人(病例来源为浙江省诸暨市中医院住院行髋关节置换术的病人)按随机对照原则,分为治疗组和对照组。手术为同一组医生操作,均采用全麻。术后治疗组给补阳还五汤加减,每天1剂,水煎,早晚分服; 对照组给拜瑞妥10 mg,每天1次口服。给药2周。观察治疗前后肢体周径变化、凝血谱变化情况,并做血管彩超检查观察血流通畅情况及有无血栓形成。结果:两组患者肢体周径变化(大腿周径增加值),术后24 h、3 d、1周、2周组间比较,差异均无统计学意义(P>0.05); 凝血酶原时间和部分凝血酶活化时间变化术后3 d、1周、2周比较,差异亦无统计学意义(P>0.05); 股静脉血流速度变化,术后1周与术前比较,差异有统计学意义(P<0.05),术后2周与术前比较,差异无统计学意义(P>0.05); 两组患者术后下肢深静脉血栓发生率比较,差异无统计学意义(P>0.05)。结论:补阳还五汤加减方能很好地预防髋关节置换术后下肢深静脉血栓形成,其临床效果与拜瑞妥在统计学上无显著差异。
Abstract:
Objective:To observe the effectiveness of Bu Yang Huan Five Decoction in prevention of deep vein thrombosis(DVT)after total hip arthroplasty.Methods:77 patients(patients underwent hip replacement operation in our hospital)operated by the same group of doctors were randomly divided into treatment group and control group,all the patients were operated by the same group of doctors under general anesthesia.Postoperative Patients in treatment group were administrated with Bu Yang Huan Five Decoction modifying soup one dose a day,morning and evening hours service; patiens in the control group took Xarelto 10 mg,once a day orally for 2 weeks.Observe limb circumference,blood coagulation function changes,hemodynamics of vessels by vascular ultrasound and check for the thrombosis before and after treatment.Results:In limb circumference variation,there was no significant difference in statistics(P>0.05)between the two groups of patients with the upper edge of the patella 15 cm thigh circumference increased value,in 24 hours,three days after operation,one week and two phase comparison; there was significant difference in statistics(P<0.05)in femoral vein hemodynamics changes of one week after operation compared with that before operation in both groups,while no difference(P>0.05)appeared between that 2 weeks after operation with that before operation.There was no significant difference in statistics(P>0.05)in the occurrence of DVT after operation between two groups.Conlusion:The Buyang Huanwu Decoction modifying can prevent DVT after THR and it shows no significant difference in clinical effectiveness with the Xarelto.

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更新日期/Last Update: 2013-02-20