[1]胡劲涛,许超,韩耀静,等.抑郁与绝经后女性骨密度的相关性研究[J].中医正骨,2013,25(02):22-24.
　HU Jin-tao*,XU Chao,HAN Yao-jing,et al.Correlation between depression and bone mineral density in postmenopausal women[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2013,25(02):22-24.
点击复制

抑郁与绝经后女性骨密度的相关性研究()
分享到：

《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第25卷
期数:
2013年02期
页码:
22-24
栏目:
临床研究
出版日期:
2013-02-20

文章信息/Info

Title:
Correlation between depression and bone mineral density in postmenopausal women
作者:
胡劲涛1; 许超2; 韩耀静2; 孙国丽2
1.浙江中医药大学第二临床医学院,浙江 杭州 310005;
2.浙江中医药大学附属第二医院,浙江 杭州 310005
Author(s):
HU Jin-tao*; XU Chao; HAN Yao-jing; SUN Guo-li.
*No.2 Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310005,Zhejiang,China
关键词:
绝经后 女性 骨密度 抑郁
Keywords:
Post-menopause; Female; Bone mineral density; Depression
摘要:
目的:探讨抑郁情志与绝经后女性腰椎骨密度的相关性。方法:收集70名受访者,采用Medilink双能X线骨密度仪测量骨密度及汉密尔顿抑郁调查量表评估抑郁值,将受访者分为骨质疏松组与非骨质疏松组进行比较分析,同时分别对两组受访者抑郁和骨密度进行相关性分析。结果:骨质疏松组与非骨质疏松组抑郁值之间存在显著差异(13.2±7.6 VS 5.2±7.1,F=-4.055,P=0.000),且骨质疏松组L1、L2、L3、L4和总体腰椎骨密度值与抑郁呈负相关,相关系数分别为-0.653(P=0.000)、-0.425(P=0.010)、-0.447(P=0.006)、-0.376(P=0.024)、-0.618(P=0.000),非骨质疏松组它们两者之间无相关性。结论:抑郁与骨密度之间存在关联性,抑郁越严重骨密度值越低,抑郁是骨质疏松症加剧的因素之一。
Abstract:
Objective:To investigate the correlation between depressive emotion and lumbar bone mineral density of the postmenopausal women.Methods:To collect 70 respondents,using Medilink dual energy X-ray absorptiometry measurements in subjects for bone mineral density and the Hamilton depression inventory to assess depression value,the respondents were divided into osteoporosis group and non-osteoporosis group to compare.Meanwhile,correlation of depression value and bone mineral density of two groups were analysised respectively.Results:The osteoporosis group and non-osteoporosis group differences in depression value(13.2±7.6 VS 5.2±7.1,F=-4.055,P=0.000),L1,L2,L3,L4 and total lumbar bone density were negative correlative with depression scores,the correlation coefficients were -0.653(P=0.000),-0.425(P=0.010),-0.447(P=0.006),-0.376(P=0.024),-0.618(P=0.000),but there was no correlation between them in osteoporosis group.Conclusion:Depression and bone mineral density have certain relationship.The more depressed people have a lower bone mineral density.Depression is one of the factors can aggravate osteoporosis.

参考文献/References:

[1] 许超,肖鲁伟,童培建,等.骨质疏松症的中医辩证分型客观化研究[J].中医正骨,2010,22(2):27-30.
[2] 许超,肖鲁伟,吴承亮.绝经后女性骨质疏松症辨证分型与抑郁焦虑的关系研究[J].中医正骨,2011,23(12):3-5.
[3] Cizza G,Primma S,Csako G.Depression as a risk factor for osteoporosis[J]. Trends Endocrinol Metab, 2009, 20: 367-373.
[4] Williams LJ,Bjerkeset O,Langhammer A,et al.The association between depressive and anxiety symptoms and bone mineral density in the general population:The HUNT Study[J].Journal of Affective Disord,2011,131(1-3):164-171.
[5] Oh SM,Kim HC,Ahn SV,et al.Association between depression and bone mineral density in community-dwelling older men and women in Korea[J].Maturitas,2012,71(2):142-146.
[6] Whooley MA,Kip KE,Cauley JA,et al.Depressive symptoms and bone mineral density in older men[J].J Geriatry Psychiatry Neurol,2004,17:88-92.

备注/Memo

备注/Memo:
基金项目:浙江省自然科学基金项目(Y2111258)
通讯作者:许超 E-mail:docxuchao@126.com
更新日期/Last Update: 2013-02-20