[1]陈大宇,曹亚飞,麦庆春,等.中药热奄包治疗膝骨关节炎的临床观察[J].中医正骨,2011,23(06):6-8.
　CHEN Da-yu*,CAO Ya-fei,MAI Qing-chun,et al.Clinical observation on the effect of traditional Chinese medicine REYANBAO on knee osteoarthritis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2011,23(06):6-8.
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中药热奄包治疗膝骨关节炎的临床观察()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第23卷
期数:
2011年06期
页码:
6-8
栏目:
临床研究
出版日期:
2011-06-30

文章信息/Info

Title:
Clinical observation on the effect of traditional Chinese medicine REYANBAO on knee osteoarthritis
作者:
陈大宇; 曹亚飞; 麦庆春; 蒋顺琬; 王业广
广东省深圳市中医院,广东 深圳 518033
Author(s):
CHEN Da-yu*; CAO Ya-fei; MAI Qing-chun; et al.*
Traditional Chinese Medical Hospital of Shenzhen City,Shenzhen 518033,Guangdong,China
关键词:
骨关节炎; 膝 中药外敷 热敷 治疗; 临床研究性
Keywords:
Osteoarthritis; knee;  External applications(TCD);  External therapies;  Therapies; investigational
摘要:
目的:观察中药热奄包外用治疗膝骨关节炎的临床疗效。方法:将符合要求的135例患者随机分为3组,每组45例。Ⅰ组采用中药热奄包外用治疗; Ⅱ组采用中药热奄包结合双氯芬酸外敷治疗; Ⅲ组单纯使用双氯芬酸外敷治疗。参照Lequesne的膝骨关节炎严重性和活动指数评估法制定评分表,分别于治疗前、治疗后2周、治疗后1个月及治疗后3个月对患者进行临床评分。结果:治疗前后不同时点之间临床评分差异有统计学意义(F=374.933,P=0.000)。3种不同治疗方法之间,差异也有统计学意义(F=8.188,P=0.000)。从各时点看,Ⅱ组治疗后2周、治疗后1个月的评分低于Ⅰ组和Ⅲ组(治疗后2周:P=0.000,P=0.000; 治疗后1个月:P=0.006,P=0.000),治疗后3个月Ⅰ、Ⅱ组评分均低于Ⅲ组(P=0.014,P=0.000); 各时点其余组间比较,差异均无统计学意义。治疗方法与时间之间存在交互效应(F=4.357,P=0.001)。结论:中药热奄包治疗膝骨关节炎短期疗效不及中药热奄包加双氯芬酸外用联合治疗,但也能从根本上改善本病的病理改变,中期疗效与其相当。
Abstract:
Objective:To observe the clinical curative effect of the external application of traditional Chinese medicine(TCM)REYANBAO on knee osteoarthritis.Methods:135 patients met the criteria were randomly divided into 3 groups,45 cases in each group.Patients in groupⅠwere administrated with the external application of TCM REYANBAO,and patients in groupⅡwere administrated with the external application of TCM REYANBAO combined with diclofenac,while the others in groupⅢwere administrated with the external application of diclofenac only.A score sheet was drawn up with reference to Lequesne knee osteoarthritis severity and activity index evaluation method,and the clinical effects were scored according to above sheet before the treatment,2 weeks,1 month and 3 months after the treatment respectively.Results:There was statistical difference in clinical scores among different time points(F=374.933,P=0.000).There was statistical difference among the 3 different treatment methods(F=8.188,P=0.000).From the view of each time point:2 weeks and 1 month after the treatment,the scores of groupⅡwere lower than those of groupⅠand groupⅢ(2 weeks after treatment:P=0.000,P=0.000; 1 month after treatment:P=0.006,P=0.000); 3 months after the treatment,the scores of groupⅠand groupⅡwere both lower than those of groupⅢ(P=0.014,P=0.000); there was no statistical difference in scores between other couple groups.There was interaction effects between treatment method and times(F=4.357,P=0.001).Conclusion:Although the short-term effects of TCM REYANBAO is not as good as that of the external application of TCM REYANBAO combined with diclofenac in the treatment of knee osteoarthritis,it can improve the pathological changes of this disease fundamentally and it has the similar intermediate-term effects to that of the above combination method.

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更新日期/Last Update: 2011-06-30