[1]凌云,王延涛,欧阳国容.关节镜术后应用止痛四物汤治疗膝骨关节炎的疗效观察[J].中医正骨,2011,23(04):6-8.
　LING Yun*,WANG Yan-tao,OUYANG Guo-rong.*.Observation on the curative effect of ZHITONG SIWU decoction(止痛四物汤)on knee osteoarthritis after arthroscopy[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2011,23(04):6-8.
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关节镜术后应用止痛四物汤治疗膝骨关节炎的疗效观察()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第23卷
期数:
2011年04期
页码:
6-8
栏目:
临床研究
出版日期:
2011-04-30

文章信息/Info

Title:
Observation on the curative effect of ZHITONG SIWU decoction(止痛四物汤)on knee osteoarthritis after arthroscopy
作者:
凌云; 王延涛; 欧阳国容
广东省广州市番禺区中医院,广东 广州 511400
Author(s):
LING Yun*; WANG Yan-tao; OUYANG Guo-rong.*
Traditional Chinese Medical Hospital of Panyu District in Guangzhou City,Guangzhou 511400,Guangdong,China
关键词:
骨关节炎; 膝 痹证 关节镜检查 止痛四物汤
Keywords:
Osteoarthritis; Knee;  Arthralgia syndrome;  Arthroscopy;  ZHITONG SIWU decoction
摘要:
目的:观察膝关节镜术后应用止痛四物汤治疗膝骨关节炎的临床疗效。方法:将62例符合标准的膝骨关节炎患者随机分为2组,每组31例。在关节镜下行关节清理术后,Ⅰ组患者口服硫酸氨基葡萄糖片,Ⅱ组患者口服中药止痛四物汤。分别于治疗前、治疗后1个月、3个月及6个月采用膝关节功能计分标准对两组患者的关节功能进行评分。结果:两组患者膝关节功能评分经重复测量方差分析,存在分组效应(F=3.553,P=0.001)和时间效应(F=4.015,P=0.001)。不同时点评分比较:治疗前和治疗后1个月两组间比较,差异无统计学意义(P=0.336,P=0.257); 治疗后3个月Ⅱ组评分高于Ⅰ组,差异有统计学意义(P=0.021); 治疗后6个月Ⅱ组评分高于Ⅰ组,差异有统计学意义(P=0.008)。结论:膝骨关节炎患者关节镜术后应用硫酸氨基葡萄糖片和止痛四物汤均能缓解膝关节疼痛、改善膝关节功能,但止痛四物汤的中期疗效优于硫酸氨基葡萄糖片。
Abstract:
Objective:To observe the curative effect of ZHITONG SIWU decoction(止痛四物汤)on knee osteoarthritis(KOA)after arthroscopy.Methods:62 KOA patients met the criteria were randomly divided into 2 groups,31 cases in each group.After arthroscopic debridement,patients in groupⅠwere administrated with glucosamine sulfate tablets(GST),while the others in groupⅡwere administrated with ZHITONG SIWU decoction(止痛四物汤).Joint functions of the patients in the 2 groups were scored according to knee function scoring criteria before treatment,1 month,3 months and 6 months after treatment respectively.Results:Repeated Measures Analysis of Variance(ANOVA)was used in analyzing the knee joint function scores of the patients in the 2 groups.The analytic result displayed that there were group effect(F=3.553,P=0.001)and time effect(F=4.015,P=0.001).The scores were compared in different time points:there was no statistical difference between the 2 groups before treatment and 1 month after treatment(P=0.336,P=0.257); 3 months after treatment,scores of groupⅡwere higher than those of groupⅠ,there was statistical difference between the 2 groups(P=0.021); 6 months after treatment,scores of groupⅡwere higher than those of groupⅠ(P=0.008).Conclusion:Although GST and ZHITONG SIWU decoction(止痛四物汤)all perform well on pain relief of knee joint and improvement of knee function for KOA patients after arthroscopic debridement,the medium-term effect of ZHITONG SIWU decoction(止痛四物汤)was better than that of GST.

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更新日期/Last Update: 2011-04-30