[1]张广飞,郑宇,纪垚垚,等.骨关节炎软骨细胞程序性死亡类型及其交互关系的研究进展[J].中医正骨,2026,38(03):66-72.
　ZHANG Guangfei,ZHENG Yu,JI Yaoyao,et al.Advances in research on the types and interactions of programmed cell death in osteoarthritis chondrocytes[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2026,38(03):66-72.
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骨关节炎软骨细胞程序性死亡类型及其交互关系的研究进展()

《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第38卷
期数:
2026年03期
页码:
66-72
栏目:
综述
出版日期:
2026-03-20

文章信息/Info

Title:
Advances in research on the types and interactions of programmed cell death in osteoarthritis chondrocytes
作者:
张广飞1; 郑宇2; 纪垚垚1; 杨虎1; 王通1; 闫泓旭1; 李豪1; 田盛2
(1.陕西中医药大学,陕西 咸阳 712046; 2.陕西省中医医院,陕西 西安 710003)
Author(s):
ZHANG Guangfei; ZHENG Yu; JI Yaoyao; YANG Hu; WANG Tong; YAN Hongxu; LI Hao; TIAN Sheng
关键词:
骨关节炎;  软骨细胞;  细胞死亡;  综述
摘要:
软骨细胞程序性死亡(programmed cell death,PCD)包括细胞凋亡、细胞焦亡、铁死亡、铜死亡及自噬性细胞死亡,在骨关节炎(osteoarthritis,OA)软骨细胞损伤、炎症微环境形成与软骨基质降解等病理变化中起关键作用。OA的发生和发展受软骨细胞PCD的调控,且各类型PCD之间存在交互关系,形成了复杂的调控网络。本文对OA软骨细胞PCD的类型及其交互关系进行了综述,为OA的靶向治疗提供了参考和新的思路。

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备注/Memo

备注/Memo:
基金项目:陕西省中医医院院级“苗圃培育计划”项目(2025-05)
通信作者:郑宇 E-mail:sxszyyygskzy@163.com
(收稿日期:2026-01-05 本文编辑:杨雅)
更新日期/Last Update: 2026-03-20