[1]张广飞,郑宇,纪垚垚,等.基于机械应力的骨质疏松症发病机制及防治策略研究进展[J].中医正骨,2026,38(06):45-49,60.
 ZHANG Guangfei,ZHENG Yu,JI Yaoyao,et al.Advances in research on pathomechanisms and preventive strategies of osteoporosis based on mechanical stress[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2026,38(06):45-49,60.
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基于机械应力的骨质疏松症发病机制及防治策略研究进展()

《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第38卷
期数:
2026年06期
页码:
45-49,60
栏目:
综述
出版日期:
2026-06-20

文章信息/Info

Title:
Advances in research on pathomechanisms and preventive strategies of osteoporosis based on mechanical stress
作者:
张广飞1郑宇2纪垚垚1杨虎1王通1闫泓旭1李豪1田盛2袁梦博1
1.陕西中医药大学,陕西 咸阳 712046; 2.陕西省中医医院,陕西 西安 710003
Author(s):
ZHANG GuangfeiZHENG YuJI YaoyaoYANG HuWANG TongYAN HongxuLI HaoTIAN ShengYUAN Mengbo
关键词:
骨质疏松 应力物理 骨代谢 综述
摘要:
骨质疏松症(osteoporosis,OP)是一种全球高发的骨骼退行性疾病。既往针对OP的研究主要围绕激素调控、钙磷代谢及维生素D信号通路等生物化学维度展开。随着骨骼生物力学研究的不断深入,机械应力在骨生长与重建中的作用受到越来越多的关注。本文从机械应力影响骨代谢的细胞与分子机制、机械应力缺失与OP的联系,以及基于机械应力的OP防治策略3个方面,系统梳理了基于机械应力的OP发病机制及防治策略的研究进展,为OP的精准防治提供了新的视角。

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备注/Memo

备注/Memo:
基金项目:陕西省中医药研究院 陕西省中医医院院级“苗圃培育计划”项目(2025-05)
通信作者:郑宇 E-mail:sxszyyygskzy@163.com
(收稿日期:2025-12-27 本文编辑:李晓乐)
更新日期/Last Update: 2026-06-20