[1]龚辉,邓奕辉,王衡新,等.TOLL样受体2、4及其介导的NF-κB信号通路参与类风湿关节 炎发病的研究进展[J].中医正骨,2018,30(07):29-31.
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TOLL样受体2、4及其介导的NF-κB信号通路参与类风湿关节 炎发病的研究进展()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第30卷
期数:
2018年07期
页码:
29-31
栏目:
综 述
出版日期:
2018-07-20

文章信息/Info

作者:
龚辉1邓奕辉2王衡新3宋志林3
(1.湖南中医药大学附属中西医结合医院,湖南 长沙 410006; 2.湖南中医药大学,湖南 长沙 410007; 3.湖南天地恒一制药有限公司,湖南 长沙 410331)
关键词:
关节炎类风湿 Toll样受体2 Toll样受体4 NF-κB 信号传导 综述
摘要:
自身免疫激活导致的炎症反应是类风湿关节炎(rheumatoid arthritis,RA)发病的关键。TOLL样受体(toll-like receptors,TLRs)中的TLR2、TLR4及其介导的NF-κΒ信号通路能诱发机体炎症反应、介导炎症因子表达,参与了RA的发病。本文对近年来关于TLR2、TLR4及其介导的NF-κB信号通路参与RA发病的研究进展进行了综述。

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备注/Memo

备注/Memo:
基金项目:湖南省自然科学基金面上项目(2017JJ2190) 通讯作者:王衡新 E-mail:942018305@qq.com
更新日期/Last Update: 2018-11-30