[1]柴乐,全仁夫,黄小龙.羟基磷灰石构建组织工程骨支架的研究进展[J].中医正骨,2018,30(01):44-46,50.
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羟基磷灰石构建组织工程骨支架的研究进展()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第30卷
期数:
2018年01期
页码:
44-46,50
栏目:
综述
出版日期:
2018-01-20

文章信息/Info

作者:
柴乐1全仁夫2黄小龙2
1.浙江中医药大学,浙江 杭州 310053; 2.浙江省杭州市萧山区中医院,浙江 杭州 311201
关键词:
羟基磷灰石类 组织工程骨 组织支架 骨缺损 综述
摘要:
组织工程骨支架作为组织工程骨研究的关键点之一,是目前骨科及创伤外科研究的热点。羟基磷灰石(hydroxyapatite,HA)是骨组织的主要无机成分,具有良好的生物相容性和骨诱导性。单纯的HA存在机械强度和韧性差等问题,不能满足人体承重部分骨代替的要求,因此人们开始转向HA复合材料支架的研究。目前已研制出了HA复合金属镁、HA复合胶原蛋白、HA复合丝素蛋白、HA复合乳酸、HA复合二氧化锆、HA复合聚己内酯等多种具有良好生物特性的HA复合材料组织工程骨支架,同时已开始应用3D打印技术制作更加复杂、具有更优异生物特性的HA组织工程骨支架。虽然HA复合材料组织工程骨支架在实验研究中已获得了成功,但要将其应用于临床还有很长的路要走。

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备注/Memo

备注/Memo:
通讯作者:全仁夫 E-mail:quanrenfu@126.com
更新日期/Last Update: 2018-06-02