[1]罗明星,刘丙根,罗文礼,等.保肢与截肢治疗后骨肉瘤患者肢体功能及生活质量的Meta分析[J].中医正骨,2017,29(07):41-45.
　LUO Mingxing,LIU Binggen,LUO Wenli,et al.Comparison of limb salvage and amputation on limb function and life quality of patients with osteosarcoma:a meta analysis[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2017,29(07):41-45.
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保肢与截肢治疗后骨肉瘤患者肢体功能及生活质量的Meta分析()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第29卷
期数:
2017年07期
页码:
41-45
栏目:
文献研究
出版日期:
2017-07-20

文章信息/Info

Title:
Comparison of limb salvage and amputation on limb function and life quality of patients with osteosarcoma:a meta analysis
作者:
罗明星1; 刘丙根1; 罗文礼1; 付有伟2; 庞清江2
1.浙江省宁波市杭州湾医院,浙江 宁波 315010; 2.浙江省宁波市第二医院,浙江 宁波 315010
Author(s):
LUO Mingxing1; LIU Binggen1; LUO Wenli1; FU Youwei2; PANG Qingjiang2
1.Hangzhou Bay Hospital of Ningbo City,Ningbo 315010,Zhejiang,China 2.The Second Hospital of Ningbo City,Ningbo 315010,Zhejiang,China
关键词:
骨肉瘤;  截肢术;  保肢治疗;  功能恢复;  生活质量;  Meta分析;  系统评价
Keywords:
Key words osteosarcoma;  amputation;  limb salvage;  recovery of function;  quality of life;  Meta-Analysis;  systematic review
摘要:
目的:系统评价保肢与截肢治疗后骨肉瘤患者的肢体功能及生活质量。方法:以计算机检索The Cochrane Library(2016年第12期)、PubMed、Ovid、Spinger Link、Elsevier、CNKI、WanFang Data 1970年1月1日至2016年12月31日所有有关比较保肢与截肢治疗后骨肉瘤患者肢体功能及生活质量的中、英文献,同时手工检索纳入文献的 参考文献。由2位研究人员独立进行文献检索、筛选,采用Cochrane协作网提供的Revman5.0软件进行Meta分析。结果:共检出文献1301篇,经筛选后最终纳入10篇文献,均为英文文献。总样本量614例,保肢治疗组350例、截肢治疗组264例。Meta分析结果显示,2组患者治疗后的多伦多保肢评分系统评分比较,差异无统计学意义[WMD=-0.23,95%CI(-0.82,0.36)]; 保肢组的简明健康状况调查表评分高于截肢组[WMD=-0.26,95%CI(-0.46,-0.06)]。结论:与截肢治疗相比,采用保肢治疗后骨肉瘤患者的生活质量更高,但肢体功能与前者相当。
Abstract:
ABSTRACT Objective:To systematically review limb function and life quality of patients with osteosarcoma after limb salvage and amputation.Methods:All the Chinese and English articles about limb function and life quality of patients with osteosarcoma after limb salvage and amputation included from January 1,1970 to December 31,2016 were retrieved from the Cochrane Library(2016,No.12),PubMed,Ovid,Spinger Link,Elsevier,China national knowledge internet and WanFang Data through computer.Meanwhile,all the references in the included articles were manual retrieved.The articles were searched and screened independently by two researchers.The articles were evaluated by using Cochrane system and a Meta-analysis was conducted by using Revman 5.0 software.Results:One thousand three hundred and one articles were searched out.After screening,10 English articles(614 patients)were included in the final analysis,350 patients in limb salvage group and 264 patients in amputation group.The result of Meta-analysis demonstrated that there was no statistical difference in posttreatment Toronto extremity salvage scores between the 2 groups(WMD=-0.23,95%CI(-0.82,0.36))and the short form 36 health survey questionnaire(SF-36)scores were higher in limb salvage group compared to amputation group(WMD=-0.26,95%CI(-0.46,-0.06)).Conclusion:The patients with osteosarcoma can obtain better life quality after limb salvage compared to amputation,while the two treatments are similar to each other in limb function.

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备注/Memo

备注/Memo:
通讯作者:庞清江 E-mail:pqjey@sina.com
更新日期/Last Update: 2017-12-29