[1]李益军,林杜峰,李庐娟,等.肌筋膜疼痛综合征与血尿酸水平的关系研究[J].中医正骨,2015,27(05):9-11.
 LI Yijun,LIN Dufeng,LI Lujuan,et al.Clinical study on the relationship between myofascial pain syndromes and blood uric acid level[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(05):9-11.
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肌筋膜疼痛综合征与血尿酸水平的关系研究()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第27卷
期数:
2015年05期
页码:
9-11
栏目:
临床研究
出版日期:
2015-05-30

文章信息/Info

Title:
Clinical study on the relationship between myofascial pain syndromes and blood uric acid level
作者:
李益军林杜峰李庐娟谢美玲郑彬方细霞
广东省东莞市石碣医院,广东 东莞 523290
Author(s):
LI YijunLIN DufengLI LujuanXIE MeilingZHENG BinFANG Xixia
The Shijie Hospital of Dongguan City,Dongguan 523290,Guangdong,China
关键词:
肌筋膜疼痛综合征 高尿酸血症 相关分析
Keywords:
myofascial pain syndromes hyperuricemia correlation analysis
摘要:
目的:探讨肌筋膜疼痛综合征(myofascial pain syndromes,MPS)与血尿酸水平的关系。方法:选取219例MPS患者,按照年龄分为18~29岁组、30~39岁组、40~49岁组和≥50岁组。测定患者的血尿酸水平、主要疼痛部位疼痛视觉模拟评分(visual analogue score,VAS)及压痛评分。分析患者血尿酸水平与其年龄、主要疼痛部位疼痛及压痛程度的关系。结果:18~29岁组40例、30~39岁组84例、40~49岁组57例,均为男性; ≥50岁组38例,男25例、女13例。4组男性患者主要疼痛部位压痛评分、疼痛VAS评分及血尿酸水平比较,组间差异均无统计学意义[(1.30±0.46)分,(1.42±0.54)分,(1.39±0.56)分,(1.76±0.66)分,χ2=9.712,P=0.121;(4.52±1.41)分,(4.48±1.81)分,(4.23±1.71)分,(5.20±1.71)分,χ2=5.940,P=0.115;(500.35±138.85)μmol·L-1,(447.81±130.97)μmol·L-1,(467.86±123.70)μmol·L-1,(455.32±101.99)μmol·L-12=4.152,P=0.246]。219例MPS患者中,138例诊断为高尿酸血症(Hyperuricemia,HUA),男126例、女12例; 18~29岁组30例、30~39岁组50例、40~49岁组37例、≥50岁组21例(男9例、女12例)。男性各年龄组HUA发生率由高至低依次为18~29岁组、40~49岁组、30~39岁组、≥50岁组。Pearson相关分析结果显示,血尿酸水平与年龄、MPS主要疼痛部位的压痛评分和疼痛VAS评分均呈正相关(r=0.425,P=0.016; r=0.496,P=0.004; r=0.402,P=0.028)。结论:MPS患者中HUA的发生率较高,且MPS患者的血尿酸水平与其年龄、疼痛及压痛程度呈正相关。
Abstract:
Objective:To explore the relationship between myofascial pain syndromes(MPS)and blood uric acid(BUA)level.Methods:Two hundred and nineteen patients with MPS were selected and divided into group A(aged 18-29 years),group B(aged 30-39 years),group C(aged 40-49 years)and group D(≥50 years old).The BUA level,visual analogue score(VAS)and tenderness score of main pain sites were measured.Meanwhile the relationship between BUA level and age,pain degree and tenderness degree of main pain sites were analyzed.Results:The patients in group A(40 cases),B(84 cases)and C(57 cases)were males,while the patients in group D(38 cases)included 25 males and 13 females.There was no statistical difference in tenderness scores and VAS of main pain sites and BUA level between the 4 groups in males(1.30+/-0.46,1.42+/-0.54,1.39+/-0.56,1.76+/-0.66 points,χ2=9.712,P=0.121; 4.52+/-1.41,4.48+/-1.81,4.23+/-1.71,5.20+/-1.71 points,χ2=5.940,P=0.115; 500.35+/-138.85.447.81+/-130.97.467.86+/-123.70,455.32+/-101.99 μmol/L,χ2=4.152,P=0.246).A total of 138 hyperuricemia(HUA)out of 219 MPS were diagnosed,including 126 males and 12 females,and 30 aged 18-29 years,50 aged 30-39 years,37 aged 40-49 years and 21 ≥50 years old(9 males and 12 females).Males had high-to-low incidence rate of HUA in group A,C, B and D.The result of Pearson correlation analysis showed that BUA level were positively correlated with ages,tenderness scores and VAS of main pain sites in patients with MPS(r=0.425,P=0.016; r=0.496,P=0.004; r=0.402,P=0.028).Conclusion:The incidence rate of HUA is high in patients with MPS,and the BUA level is positively correlated with ages and the degree of pain and tenderness.

参考文献/References:

[1] Schlesinger N.Dietary factors and hyperuricaemia[J].Curr Pharm Des,2005,11(32):4133-4138.
[2] 曾成,王宁华.肌筋膜疼痛综合征的治疗进展[J].中国康复理论与实践,2014,20(3):245-249.
[3] 江亿平.慢性软组织损害的概念与纤维肌痛综合征及肌筋膜疼痛综合征的比较[J].中国临床康复,2005,9(30):204-206.
[4] 查和萍,谢健周,范志勇,等.肌筋膜疼痛综合征中医研究进展[J].辽宁中医药大学学报,2010,12(12):22-24.
[5] 尤春景.肌肉疼痛综合征的诊断和治疗(待续)[J].国外医学:物理医学与康复学分册,1996,16(4):145-149.
[6] Wall PD.疼痛学[M].3版.赵宝昌,崔秀云,译.沈阳:辽宁教育出版社,2000:393-395.
[7] Simons DG,Travell J.Myofascial trigger points,a possible explanation[J].Pain,1981,10(1):106-109.
[8] Akbas EM,Timuroglu A,Ozcicek A,et al.Association of uric acid, atherogenic index of plasma and albuminuria in diabetes mellitus[J].Int J Clin Exp Med,2014,7(12):5737-5743.
[9] Aarflot T,Laerum E,Bruusgaard D.Uric acid and chronic musculoskeletal complaints[J].Scand J Rheumatol,1992,21(6):277-282.
[10] Andersson HI,Ejlertsson G,Leden I,et al.Characteristics of subjects with chronic pain, in relation to local and widespread pain report.A prospective study of symptoms,clinical findings and blood tests in subgroups of a geographically defined population[J].Scand J Rheumatol,1996,25(3):146-154.
[11] Krishnan E,Pandya BJ,Chung L,et al.Hyperuricemia and the risk for subclinical coronary atherosclerosis—data from a prospective observational cohort study[J].Arthritis Res Ther,2011,13(2):R66.
[12] 张榜,崔炎,吴建萍,等.尿酸盐结晶在手足部位的沉积规律[J].中国中西医结合外科杂志,2013,19(6):627-630.
[13] 熊辉,曲良烨,向黎黎,等.痛风性关节炎湿热证病证结合模型的建立[J].中医正骨,2014,26(3):14-20.
[14] 陈枫,王敏,叶湛,等.关节镜技术在急性膝痛风性关节炎诊治中的应用[J].中医正骨,2013,25(5):47-49.
[15] 李国春,巫开文.2010年某院健康体检人群高尿酸血症流行性分析[J].中国医药指南,2011,34(34):169-170.

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备注/Memo

备注/Memo:
2015-01-04收稿 2015-03-02修回
基金项目:东莞市科技计划一般项目(201410515000171)
通讯作者:林杜峰 E-mail:doctorlin@163.com
更新日期/Last Update: 2015-05-30