[1]向黎黎,熊辉,陆小龙,等.中药治疗痛风用药规律的文献研究[J].中医正骨,2015,27(12):46-49.
　XIANG Lili,XIONG Hui,LU Xiaolong,et al.Literature research on medication rule of Traditional Chinese Medicine for treatment of gout[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2015,27(12):46-49.
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中药治疗痛风用药规律的文献研究()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第27卷
期数:
2015年12期
页码:
46-49
栏目:
文献研究
出版日期:
2015-12-30

文章信息/Info

Title:
Literature research on medication rule of Traditional Chinese Medicine for treatment of gout
作者:
向黎黎1; 熊辉1; 陆小龙1; 齐新宇2; 郭玉星2; 李腾龙1; 周彪2
1.湖南中医药大学第二附属医院,湖南 长沙 410005;
2.湖南中医药大学,湖南 长沙 410208
Author(s):
XIANG Lili1; XIONG Hui1; LU Xiaolong1; QI Xinyu2; GUO Yuxing2; LI Tenglong1; ZHOU Biao2
1.The Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha 410208,Hunan,China
2.Hunan University of Traditional Chinese Medicine,Changsha 410208,Hunan,China
关键词:
痛风;  中药疗法;  抗痛风药(中药)
Keywords:
gout;  drug therapy(TCD);  gout suppressants(TCD)
摘要:
目的:探讨中药治疗痛风的用药规律。方法:以“中药”“痛风”“痛风性关节炎”“高尿酸血症”为检索词从中国知网和湖南中医药大学图书馆数据库中检索2005—2014年有关中药治疗痛风的期刊文献。对文献中记载的证型、方名、药名、药性、药味、归经、功效及现代药理作用进行统计。结果:共检索出符合要求的文献221篇,作者地域分布南方省份125篇、北方省份96篇。证型以湿热蕴结证最多见,其次为瘀热阻滞证。221篇文献涉及药物210味,用药总频次2251次,用药频次在10次以上的单味药59味,累计频次1947次,用药频次最高的5味药依次为牛膝、黄柏、薏苡仁、土茯苓和苍术。59味高频次药物中,药性以寒、温、平为主,药味以苦、甘、辛为主,归经以肝、脾、肺、肾、胃经为主,功效以清热、活血化瘀、利水渗湿和祛风湿为主。59味高频次药物中,涉及现代药理作用38项,主要有抑菌、镇痛、抗炎、镇静、利尿、降压、解热、抗凝等。结论:治疗痛风的中药组方中,药性以寒、温、平为主,药味以苦、甘、辛为主,功效以清热、活血化瘀、利水渗湿和祛风湿为主,多归于肝、脾、肺、肾、胃经,主要有抑菌、镇痛、抗炎、镇静、利尿、降压、解热、抗凝等作用。
Abstract:
Objective:To explore the medication rule of Traditional Chinese Medicine in the treatment of gout.Methods:The Boolean logical combination of traditional Chinese medicine,gout,gouty arthritis and hyperuricemia were used as index terms to retrieve all the periodical literatures of traditional Chinese medicine for treatment of gout included from 2005 to 2014 from China national knowledge internet and library database of Hunan University of Traditional Chinese Medicine,and then the type of SYMPTOM COMPLEX,name of prescription(TCD),name of drug,drug properties,drug flavour,meridian distribution,clinical effect and modern pharmacological action recorded in the literatures were statistically analyzed.Results:Two hundred and twenty-one literatures which met the requirements were searched out,and authors of 125 literatures came from southern province while authors of 96 literatures came from northern province.The most common type of SYMPTOM COMPLEX was DAMPNESS-HEAT STAGNATION,and STAGNATED HEAT STAGNATION came next.Two hundred and twenty-one literatures included 210 drugs and total frequency of drugs was 2251.There were 59 single drugs which frequency of drug was above 10 and the cumulative frequency was 1947.The top 5 drugs with high frequency of drug included twotoothed achyranthes root,phellodendron amurense,coix seed,glabrous greenbrier rhizome and rhizoma atractylodis in turn.For the 59 drugs with high frequency of drug,the drug properties presented mainly with cold,warm and normal; the drug flavours presented mainly with bitter,sweet and pungent; the meridian distributions presented mainly with liver meridian,spleen meridian,lung meridian,kidney meridian and stomach meridian; the clinical effects presented mainly with clearing heat,activating blood and resolving stasis,removing dampness and promoting diuresis and dispelling wind-damp; and 38 modern pharmacological actions of the 59 drugs presented mainly with bacteriostasis,analgesia,anti-inflammatory,sedation,diuresis,depressurization,antipyretic and anticoagulation.Conclusion:For Traditional Chinese Drugs for treatment of gout,the drug properties present mainly with cold,warm and normal; the drug flavours present mainly with bitter,sweet and pungent; the clinical effects present mainly with clearing heat,activating blood and resolving stasis,removing dampness and promoting diuresis and dispelling wind-damp; the meridian distributions present mainly with liver meridian,spleen meridian,lung meridian,kidney meridian and stomach meridian; and the modern pharmacological actions of the drugs present mainly with bacteriostasis,analgesia,anti-inflammatory,sedation,diuresis,depressurization,antipyretic and anticoagulation..

参考文献/References:

[1] 薛耀明,李晨钟.痛风的诊断与治疗[M].北京:人民军医出版社,2003.
[2] 陆再英,钟南山.内科学[M].7版.北京:人民卫生出版社,2008.
[3] 齐新宇,董大立,熊辉,等.蠲痹历节清方治疗急性痛风性关节炎湿热证疗效观察[J].湖南中医药大学学报,2014,34(5):42-44.
[4] 向黎黎,熊辉,李腾龙,等.蠲痹历节清方治疗急性期湿热蕴结型痛风性关节炎31例[J].湖南中医杂志,2015,31(2):14-16.
[5] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:31.
[6] 国家药典委员会.中华人民共和国药典[M].2010年版.北京:中国医药科技出版社,2010.
[7] 高学敏.中药学[M].7版.北京:中国中医药出版社,2007.
[8] 葛瑞英.云南(部分)地区痛风中医发病学与证候学规律研究[D].昆明:云南中医学院,2007.
[9] 熊辉,姜国勇,胡楠,等.痛风性关节炎中医证素及证型的聚类研究[J].中医正骨,2011,23(11):26-28.
[10] 杨梅,李琳荣,王雪梅,等.痛风的临床文献研究[J].山西中医学院学报,2007,8(6):2-3.
[11] 王迎春,哈朝晖,刘臣.辨证分型治疗痛风性关节炎的临床应用[J].辽宁中医杂志,2007,34(12):1767.
[12] 党万太,周京国,谢文光,等.不同中医证型痛风患者的临床指标对比分析及其意义[J].中国中西医结合杂志,2013,33(10):1323-1327.
[13] 王先敏,马丽.高尿酸血症用药的性味归经规律研究[J].中华中医药杂志,2011,26(10):2238-2240.
[14] 张荣坤.痛风病的证治与方剂配伍规律研究[D].南京:南京中医药大学,2009.
[15] 徐熠,徐玲玲,刘静,等.中药治疗慢性痛风性关节炎的规律及其Logistic回归分析[J].世界临床药物,2013,34(8):469-472.

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备注/Memo

备注/Memo:
2015-09-08收稿 2015-11-02修回
基金项目:湖南省中医药科研计划项目(201411); 湖南省教育厅科研项目(13C680)
通讯作者:熊辉 E-mail:xh_hn@sina.com
更新日期/Last Update: 2015-12-30