[1]刘成林,吴尧昆,付佳豪,等.MXene材料在骨组织工程领域应用的研究进展[J].中医正骨,2025,37(04):61-67.
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MXene材料在骨组织工程领域应用的研究进展()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第37卷
期数:
2025年04期
页码:
61-67
栏目:
综述
出版日期:
2025-04-20

文章信息/Info

作者:
刘成林吴尧昆付佳豪宋伟陈浩席洪钟刘锌孙光权杜斌
南京中医药大学附属医院,江苏 南京 210029
关键词:
组织工程 MXene材料 骨缺损 骨再生 骨疾病感染性 骨肿瘤 综述
摘要:
MXene材料是一种新型二维材料,因其优良的生物相容性、导电性、光热转换能力及生物降解性,在骨组织工程领域展现出广阔的应用前景。MXene材料通过调控成骨相关基因表达、调节免疫微环境、利用光热效应、导电性及声动力学效应等多种机制促进骨再生。此外,MXene材料具有抗菌和抗骨肿瘤作用,其光热效应和促进活性氧释放的能力可有效杀灭细菌和肿瘤细胞,同时借助优异的载药性实现药物精准释放。尽管MXene材料在骨组织工程中具有良好的应用前景,但其长期生物安全性、降解产物的细胞毒性等潜在风险仍需进一步研究。未来,通过优化制备工艺和解决降解相关问题,MXene材料有望成为一种多功能的骨组织工程材料,为骨缺损修复、抗感染及骨肿瘤治疗提供创新性解决方案。本文对MXene材料在骨再生、抗菌和抗骨肿瘤等方面的研究进展进行了综述。

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备注/Memo

备注/Memo:
基金项目:江苏省中医药管理局面上项目(MS2023023)
通讯作者:杜斌 E-mail:fsyy00608@njucm.edu.cn
更新日期/Last Update: 1900-01-01