[1]孙晓辉,赵斌,刘洋,等.负载microRNA-27b-骨髓间充质干细胞来源外泌体的软骨细胞-聚乳酸羟基乙酸共聚物骨软骨复合体移植治疗软骨缺损的实验研究[J].中医正骨,2021,33(01):1-14.
 SUN Xiaohui,ZHAO Bin,LIU Yang,et al.MicroRNA-27b-bone marrow mesenchymal stem cell derived exosomes-laden chondrocytes-poly(lactic-co-glycolic acid)osteochondral complex transplantation for treatment of osteochondral defects:an experimental study[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2021,33(01):1-14.
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负载microRNA-27b-骨髓间充质干细胞来源外泌体的软骨细胞-聚乳酸羟基乙酸共聚物骨软骨复合体移植治疗软骨缺损的实验研究()
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《中医正骨》[ISSN:1001-6015/CN:41-1162/R]

卷:
第33卷
期数:
2021年01期
页码:
1-14
栏目:
基础研究
出版日期:
2021-01-20

文章信息/Info

Title:
MicroRNA-27b-bone marrow mesenchymal stem cell derived exosomes-laden chondrocytes-poly(lactic-co-glycolic acid)osteochondral complex transplantation for treatment of osteochondral defects:an experimental study
作者:
孙晓辉赵斌刘洋崔明星
(新乡医学院第一附属医院,河南 卫辉 453100)
Author(s):
SUN XiaohuiZHAO BinLIU YangCUI Mingxing
The First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan,China
关键词:
软骨 软骨细胞 骨髓 间质干细胞 外泌体 微RNAs 大鼠 动物实验
Keywords:
cartilage chondrocytes bone marrow mesenchymal stem cells exosomes microRNAs rats animal experimentation
摘要:
目的:探讨负载microRNA-27b(miR-27b)-骨髓间充质干细胞(bone marrow mesenchymal stem cell,BMSC)来源外泌体(exosomes,exo)的软骨细胞(chondrocytes,chon)-聚乳酸羟基乙酸共聚物[poly(lactic-co-glycolic acid),PLGA]骨软骨复合体移植治疗软骨缺损的效果及作用机制。等
Abstract:
To explore the curative effects and mechanisms of action of microRNA-27b(miR-27b)-bone marrow mesenchymal stem cell(BMSC)derived exosomes(exo)-laden chondrocytes(chon)-poly(lactic-co-glycolic acid)(PLGA)osteochondral complex transplantation for treatment of osteochondral defects.et al

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备注/Memo

备注/Memo:
基金项目:河南省医学科技攻关计划项目(201602150)
通讯作者:刘洋 E-mail:450584560@qq.com
更新日期/Last Update: 2021-01-20